IRE1

  • 阻害剤の選択性比較
  • 溶解度
カタログ番号 製品カタログ 溶解度(25°C)
DMSO アルコール
S7272 4μ8C <1 mg/mL 19 mg/mL <1 mg/mL
S7771 STF-083010 <1 mg/mL 63 mg/mL <1 mg/mL
S8286 MKC-3946 <1 mg/mL 38 mg/mL 3 mg/mL
S8658 kira6 <1 mg/mL 60 mg/mL 60 mg/mL
製品コード 製品説明 文献中の使用例 お客様のフィードバック
S7272

4μ8C

4μ8C is a potent and selective IRE1 Rnase inhibitor with IC50 of 76 nM.

S7771

STF-083010

STF-083010 is a specific IRE1α endonuclease inhibitor without affecting its kinase activity.

S8286

MKC-3946

MKC3946 is a potent and soluble IRE1α endoribonuclease domain inhibitor which triggered modest growth inhibition in multiple myeloma cell lines, without toxicity in normal mononuclear cells.

S8658

kira6

Tags: IRE1 inhibitor | IRE1 modulator | IRE1 stress