OX Receptor

亜型選択性的な製品

OX1 receptor OX2 receptor

シグナル伝達経路

OX Receptor製品

All (6)
OX Receptor拮抗剤(6)
新製品

製品コード	製品名称	製品説明	文献中Selleckの製品使用例	お客様のフィードバック
S2160	Almorexant HCl	Almorexant HCl (ACT-078573) is an orally active, dual orexin receptor antagonist with IC50 of 6.6 nM and 3.4 nM for OX1 and OX2 receptor, respectively. Phase 3.	Cell Rep, 2022, 40(5):111153 Cell Rep, 2020, 31(11):107779 Am J Physiol Heart Circ Physiol, 2017, 312(4):H808-H817
S7585	SB-334867	SB-334867 is a selective orexin-1 (OX1) receptor antagonist.	J Neuroinflammation, 2020, 17(1):187 Med Sci Monit, 2019, 25:2886-2895
S1545	SB408124	SB408124 is a non-peptide antagonist for OX1 receptor with K_i of 57 nM and 27 nM in both whole cell and membrane, respectively, exhibits 50-fold selectivity over OX2 receptor.	Nat Chem Biol, 2017, 13(2):235-242
E0107	EMPA	EMPA is a selective OX2 receptor antagonist and binds to human and rat OX2-HEK293 membranes with Kd values of 1.1 and 1.4 nM respectively.	Oxid Med Cell Longev, 2022, 2022:1122494
S6726	MK1064	MK1064 is a selective orexin 2 receptor antagonist (2-SORA) with an IC50 of 18 nM.
S6717	TCS-OX2-29	TCX-OX2-29 is a OX2R antagonist (pKi = 7.5) that exhibits >250-fold selectivity for hOX2R compared with hOX1R (IC50s = 40 nM and >10,000 nM, respectively).
S2160	Almorexant HCl	Almorexant HCl (ACT-078573) is an orally active, dual orexin receptor antagonist with IC50 of 6.6 nM and 3.4 nM for OX1 and OX2 receptor, respectively. Phase 3.	Cell Rep, 2022, 40(5):111153 Cell Rep, 2020, 31(11):107779 Am J Physiol Heart Circ Physiol, 2017, 312(4):H808-H817
S7585	SB-334867	SB-334867 is a selective orexin-1 (OX1) receptor antagonist.	J Neuroinflammation, 2020, 17(1):187 Med Sci Monit, 2019, 25:2886-2895
S1545	SB408124	SB408124 is a non-peptide antagonist for OX1 receptor with K_i of 57 nM and 27 nM in both whole cell and membrane, respectively, exhibits 50-fold selectivity over OX2 receptor.	Nat Chem Biol, 2017, 13(2):235-242
E0107	EMPA	EMPA is a selective OX2 receptor antagonist and binds to human and rat OX2-HEK293 membranes with Kd values of 1.1 and 1.4 nM respectively.	Oxid Med Cell Longev, 2022, 2022:1122494
S6726	MK1064	MK1064 is a selective orexin 2 receptor antagonist (2-SORA) with an IC50 of 18 nM.
S6717	TCS-OX2-29	TCX-OX2-29 is a OX2R antagonist (pKi = 7.5) that exhibits >250-fold selectivity for hOX2R compared with hOX1R (IC50s = 40 nM and >10,000 nM, respectively).

OX Receptor阻害剤の選択性比較

Tags: OX Receptor inhibitor|OX Receptor agonist|OX Receptor activator|OX Receptor inducer|OX Receptor antagonist|OX Receptor signaling pathway|OX Receptor assay kit