テロメラーゼ

シグナル伝達経路

研究分野

  • 阻害剤の選択性比較
  • 溶解度
カタログ番号 製品カタログ 溶解度(25°C)
DMSO アルコール
S1186 BIBR 1532 <1 mg/mL 66 mg/mL 3 mg/mL
S1319 Costunolide <1 mg/mL 47 mg/mL 1 mg/mL
S2250 (-)-Epigallocatechin Gallate 23 mg/mL 72 mg/mL 83 mg/mL
S4981 Cyclogalegenol <1 mg/mL 98 mg/mL 19 mg/mL
S3894 Cycloastragenol -1 mg/mL 98 mg/mL -1 mg/mL
S8118 RHPS 4 methosulfate <1 mg/mL 91 mg/mL <1 mg/mL
製品コード 製品説明 文献中の使用例 お客様のフィードバック
S1186

BIBR 1532

BIBR 1532 is a potent, selective, non-competitive telomerase inhibitor with IC50 of 100 nM in a cell-free assay. No inhibition of DNA and RNA polymerases, including HIV reverse transcriptase were observed at concentrations vastly exceeding the IC50 for telomerase.

S1319

Costunolide

Costunolide, a natural sesquiterpene compound with multiple biological activities; inhibits FPTase with IC50 of 20 μM, also inhibits telomerase with IC50 of 65-90 μM.

S2250

(-)-Epigallocatechin Gallate

(-)-Epigallocatechin Gallate(EGCG) is the main catechin extraction of green tea that inhibits telomerase and DNA methyltransferase. EGCG blocks the activation of EGF receptors and HER-2 receptors. ECGG inhibits fatty acid synthase and glutamate dehydrogenase activity.

S4981

Cyclogalegenol

S3894

Cycloastragenol

Cycloastragenol is a saponin comprising a group of oil glucosides naturally present in a number of plants. It is a potent telomerase activator in neuronal cells.

S8118

RHPS 4 methosulfate

RHPS4 is a potent inhibitor of Telomerase at submicromolar.