テロメラーゼ

シグナル伝達経路

研究分野

  • 阻害剤の選択性比較
  • 溶解度
カタログ番号 製品カタログ 溶解度(25°C)
DMSO アルコール
S1186 BIBR 1532 <1 mg/mL 66 mg/mL 3 mg/mL
S1319 Costunolide <1 mg/mL 47 mg/mL 1 mg/mL
S2250 (-)-Epigallocatechin Gallate 23 mg/mL 72 mg/mL 83 mg/mL
S4981 Cyclogalegenol <1 mg/mL 98 mg/mL 19 mg/mL
S3894 Cycloastragenol -1 mg/mL 98 mg/mL -1 mg/mL
S8118 RHPS 4 methosulfate <1 mg/mL 91 mg/mL <1 mg/mL
製品コード 製品説明 文献中の使用例 お客様のフィードバック
S1186

BIBR 1532

BIBR 1532 is a potent, selective, non-competitive telomerase inhibitor with IC50 of 100 nM in a cell-free assay. No inhibition of DNA and RNA polymerases, including HIV reverse transcriptase were observed at concentrations vastly exceeding the IC50 for telomerase.

S1319

Costunolide

Costunolide, a natural sesquiterpene compound with multiple biological activities; inhibits FPTase with IC50 of 20 μM, also inhibits telomerase with IC50 of 65-90 μM.

S2250

(-)-Epigallocatechin Gallate

(-)-Epigallocatechin Gallate(EGCG) is the main catechin extraction of green tea that inhibits telomerase and DNA methyltransferase. EGCG blocks the activation of EGF receptors and HER-2 receptors. ECGG inhibits fatty acid synthase and glutamate dehydrogenase activity.

S4981

Cyclogalegenol

Cyclogalegenol, the aglycone derivative of astragaloside A, is found in various species of Astragalus and may activate telomerase.

S3894

Cycloastragenol

Cycloastragenol is a saponin comprising a group of oil glucosides naturally present in a number of plants. It is a potent telomerase activator in neuronal cells.

S8118

RHPS 4 methosulfate

RHPS4 is a potent inhibitor of Telomerase at submicromolar.