受注:045-509-1970 |
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Synonyms | Calcidiol, Didrogyl, Hidroferol, 25-hydroxyvitamin D3, 25-Hydroxycholecalciferol | Storage (From the date of receipt) |
3 years -20°C powder 1 years -80°C in solvent |
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化学式 | C27H44O2 |
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分子量 | 400.64 | CAS No. | 19356-17-3 | |
Solubility (25°C)* | 体外 | DMSO | 80 mg/mL (199.68 mM) | |
Ethanol | 80 mg/mL (199.68 mM) | |||
Water | Insoluble | |||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
製品説明 | Calcifediol (Calcidiol, Didrogyl, Hidroferol, 25-hydroxyvitamin D3, 25-Hydroxycholecalciferol) is a major circulating metabolite of vitamin D3 and acts as a competitive inhibitor with an apparent Ki of 3.9 μM. It also suppresses PTH secretion and mRNA (ED50=2 nM). |
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Data from [Data independently produced by , , Br J Pharmacol, 2017, 174(16):2636-2651]
Vitamin D supplementation is effective for olanzapine-induced dyslipidemia [ Front Pharmacol, 2023, 14:1135516] | PubMed: 36895943 |
Vitamin D3 suppresses the cholesterol homeostasis pathway in patient-derived glioma cell lines [ FEBS Open Bio, 2023, 13(9):1789-1806] | PubMed: 37489660 |
Vitamin D3 suppresses the cholesterol homeostasis pathway in patient-derived glioma cell lines [ FEBS Open Bio, 2023, 13(9):1789-1806] | PubMed: 37489660 |
FDA-Approved Drug Screening for Compounds That Facilitate Hematopoietic Stem and Progenitor Cells (HSPCs) Expansion in Zebrafish [ Cells, 2021, 10(8)2149] | PubMed: 34440919 |
Vitamin D Regulates MerTK-Dependent Phagocytosis in Human Myeloid Cells [ J Immunol, 2020, ji2000129] | PubMed: 32540991 |
Vitamin D 3 Modulates Yellow Catfish (Pelteobagrus Fulvidraco) Immune Function in Vivo and in Vitro and This Involves the Vitamin D 3/VDR-type I Interferon Axis [ Dev Comp Immunol, 2020, 107:103644] | PubMed: 32061641 |
Roles of Vitamin D and Its Receptor in the Proliferation and Apoptosis of Luteinised Granulosa Cells in the Goat [ Reprod Fertil Dev, 2020, 32(3):335-348] | PubMed: 31708013 |
1,25‑Dihydroxyvitamin D3 enhances the susceptibility of anaplastic thyroid cancer cells to adriamycin‑induced apoptosis by increasing the generation of reactive oxygen species [ Mol Med Rep, 2019, 20(3):2641-2648] | PubMed: 31524258 |
Temperature-dependent vitamin D signaling regulates developmental trajectory associated with diapause in an annual killifish [ Proc Natl Acad Sci U S A, 2018, 115(50):12763-12768] | PubMed: 30446615 |
Potential Use of 1-25-dihydroxyvitamin D in the Diagnosis and Treatment of Papillary Thyroid Cancer [ Med Sci Monit, 2018, 24:1614-1623] | PubMed: 29553126 |
長期の保管のために-20°Cの下で製品を保ってください。
人間や獣医の診断であるか治療的な使用のためにでない。
各々の製品のための特定の保管と取扱い情報は、製品データシートの上で示されます。大部分のSelleck製品は、推薦された状況の下で安定です。製品は、推薦された保管温度と異なる温度で、時々出荷されます。長期の保管のために必要とされてそれと異なる温度で、多くの製品は、短期もので安定です。品質を維持するが、夜通しの積荷のために最も経済的な貯蔵状況を用いてあなたの送料を保存する状況の下に、製品が出荷されることを、我々は確実とします。製品の受領と同時に、製品データシートの上で貯蔵推薦に従ってください。