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Synonyms | Cefalexin | Storage (From the date of receipt) |
3 years -20°C powder 1 years -80°C in solvent |
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化学式 | C16H17N3O4S |
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分子量 | 347.39 | CAS No. | 15686-71-2 | |
Solubility (25°C)* | 体外 | DMSO | 1 mg/mL (2.87 mM) | |
Water | 0.7 mg/mL (2.01 mM) | |||
Ethanol | Insoluble | |||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
製品説明 | Cephalexin (Cefalexin) is an antibiotic that can treat a number of bacterial infections. |
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in vitro | Cephalexin uptake by human MATE1-expressing human embryonic kidney 293 cells exhibits saturable kinetics with K(m) = 5.9 mM and a bell-shaped pH profile with a maximum at pH 7.0. [1] Cephalexin results in overestimation of glucose concentration, but only in the samples that contain the highest antimicrobial concentration (2,400microg/mL) and only for the tablet. [2] Cephalexin increases the activity of superficial mucous cells and orifice mucous cells of gastric glands, and inhibits the activity of cervix mucous cells. [3] |
in vivo | Cephalexin causes a slight prolongation of 1-stage prothrombin time (PT) and activated partial thromboplastin time (PTT) and slight decrease in fibrinogen concentration in healthy dogs. Cephalexin causes a significant increase in 1-stage PT and activated PTT, amoxicillin causes a significant increase in activated PTT, and enrofloxacin causes a significant decrease in fibrinogen concentration. [4] Cephalexin results in high numbers of E. coli producing plasmid-mediated CMY-2 β-lactamase at the end of the treatment period in dogs. [5] |
The RARS-MAD1L1 Fusion Gene Induces Cancer Stem Cell-like Properties and Therapeutic Resistance in Nasopharyngeal Carcinoma [Zhong Q, et al. Clin Cancer Res, 2018, 24(3):659-673] | PubMed: 29133573 |
MYC is a positive regulator of choline metabolism and impedes mitophagy-dependent necroptosis in diffuse large B-cell lymphoma [Xiong J, et al. Blood Cancer J, 2017, 10.1038/bcj.2017.61] | PubMed: 28686226 |
c-Myc is Required for BRAFV600E-Induced Epigenetic Silencing by H3K27me3 in Tumorigenesis [Qu Y, et al. Theranostics, 2017, 7(7):2092-2107] | PubMed: 28656062 |
Drug discovery using clinical outcome-based Connectivity Mapping: application to ovarian cancer. [Raghavan R, et al. BMC Genomics, 2016, 19;17(1):811] | PubMed: 27756228 |
長期の保管のために-20°Cの下で製品を保ってください。
人間や獣医の診断であるか治療的な使用のためにでない。
各々の製品のための特定の保管と取扱い情報は、製品データシートの上で示されます。大部分のSelleck製品は、推薦された状況の下で安定です。製品は、推薦された保管温度と異なる温度で、時々出荷されます。長期の保管のために必要とされてそれと異なる温度で、多くの製品は、短期もので安定です。品質を維持するが、夜通しの積荷のために最も経済的な貯蔵状況を用いてあなたの送料を保存する状況の下に、製品が出荷されることを、我々は確実とします。製品の受領と同時に、製品データシートの上で貯蔵推薦に従ってください。