受注:045-509-1970 |
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Synonyms | Terramycin | Storage (From the date of receipt) |
3 years -20°C powder 1 years -80°C in solvent |
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化学式 | C22H24N2O9 |
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分子量 | 460.43 | CAS No. | 79-57-2 | |
Solubility (25°C)* | 体外 | DMSO | 92 mg/mL (199.81 mM) | |
Ethanol | 10 mg/mL (21.71 mM) | |||
Water | Insoluble | |||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
製品説明 | Oxytetracycline(Terramycin) is a broad-spectrum tetracycline antibiotic, used to treat infections with bacteria. |
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in vivo | Oxytetracycline (200 mg/kg for 15 days) results a significant elevation in serum hepatospecific markers such as aspartate transaminase, alanine transaminase, alkaline phosphatase, lactate dehydrogenase, and bilirubin and the levels of lipid peroxidation markers (thiobarbituric acid reactive substances (TBARS) and lipid hydroperoxides) in rat liver. Oxytetracycline also causes a significant reduction in the activities of superoxide dismutase, catalase, glutathione peroxidase, reduced glutathione (GSH), vitamin C and vitamin E in rat liver. Oxytetracycline (200 mg/kg) combined with Naringenin (50 mg/kg b.w.t.) significantly decreases the activities of serum aspartate transaminase, alanine transaminase, alkaline phosphatase, lactate dehydrogenase and the levels of bilirubin along with significant decrease in the levels of lipid peroxidation markers in the rat liver. [1] Oxytetracycline (200 mg/kg, oral for 15 days) produces hepatic damage as manifested by a significant increase in serum hepatic markers namely aspartate transaminase (AST), alanine transaminase (ALT), alkaline phosphatase (ALP), lactate dehydrogenase (LDH), bilirubin and increases plasma and hepatic lipid peroxidation indices (TBARS and hydroperoxide) in rats. Oxytetracycline significantly decreases the levels of enzymatic antioxidants namely superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPx). [2] |
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Data from [Data independently produced by , , Front Microbiol, 2016, 7: 1765.]
Antiretroviral Drugs Alter the Content of Extracellular Vesicles from HIV-1-Infected Cells [ Sci Rep, 2018, 8(1):7653] | PubMed: 29769566 |
Ebola VP40 in Exosomes Can Cause Immune Cell Dysfunction. [Pleet ML, et al. Front Microbiol, 2016, 7: 1765] | PubMed: 27872619 |
長期の保管のために-20°Cの下で製品を保ってください。
人間や獣医の診断であるか治療的な使用のためにでない。
各々の製品のための特定の保管と取扱い情報は、製品データシートの上で示されます。大部分のSelleck製品は、推薦された状況の下で安定です。製品は、推薦された保管温度と異なる温度で、時々出荷されます。長期の保管のために必要とされてそれと異なる温度で、多くの製品は、短期もので安定です。品質を維持するが、夜通しの積荷のために最も経済的な貯蔵状況を用いてあなたの送料を保存する状況の下に、製品が出荷されることを、我々は確実とします。製品の受領と同時に、製品データシートの上で貯蔵推薦に従ってください。