Cetylpyridinium Chloride

製品コードS4172 バッチS417201

印刷

化学情報

 Chemical Structure Synonyms CPC Storage
(From the date of receipt)
3 years -20°C powder
1 years -80°C in solvent
化学式

C21H38N.Cl

分子量 339.99 CAS No. 123-03-5
Solubility (25°C)* 体外 DMSO 68 mg/mL (200.0 mM)
Water 68 mg/mL (200.0 mM)
Ethanol 68 mg/mL (200.0 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

溶剤液(一定の濃度)を調合する

生物活性

製品説明 Cetylpyridinium chloride(CPC) is a cationic quaternary ammonium compound used as oropharyngeal antiseptic.
in vitro

Cetylpyridinium chloride (CPC) as active ingredient of antiseptic oral mouthrinses has a broad antimicrobial spectrum with a rapid bactericidal effect on gram-positive pathogens and a fungicide effect on yeasts in particular. Application of CPC at a concentration of 0.05% as a mouthrinse results in an immediate reduction in bacterial counts of 2.0 to 2.5 log steps (which is adequate to > 99%). This reverts to about 1 log step (= 90%) 1 h after application. The ability of CPC to inhibit plaque and thereby reduce gingivitis is assured. In comparison to chlorhexidine, CPC has a lower residual effect, and as a result a lesser effect against plaque and gingivitis. The efficacy of CPC against oropharyngeal candidiasis is assured. CPC mouthrinses can significantly reduce infectious aerosols in dental practice, thereby protecting both staff and the patient. The balance of intra-oral bacterial flora is not disturbed even in the case of relatively long-term use of CPC (up to six weeks). [1]

in vivo

Cetylpyridinium chloride increases the risk of severe allergic reactions, such as swelling of the mouth, face, lips or tongue, labored breathing, rashes, and hives. Ingesting high concentrations of cetylpyridinium chloride can lead to lung damage. Cetylpyridinium chloride is toxic if swallowed or inhaled. [2]

プロトコル(参考用のみ)

Selleckの高級品が、幾つかの出版された研究調査結果(以下を含む)で使われた:

Masitinib Inhibits Hepatitis A Virus Replication [ Int J Mol Sci, 2023, 24(11)9708] PubMed: 37298659

長期の保管のために-20°Cの下で製品を保ってください。

人間や獣医の診断であるか治療的な使用のためにでない。

各々の製品のための特定の保管と取扱い情報は、製品データシートの上で示されます。大部分のSelleck製品は、推薦された状況の下で安定です。製品は、推薦された保管温度と異なる温度で、時々出荷されます。長期の保管のために必要とされてそれと異なる温度で、多くの製品は、短期もので安定です。品質を維持するが、夜通しの積荷のために最も経済的な貯蔵状況を用いてあなたの送料を保存する状況の下に、製品が出荷されることを、我々は確実とします。製品の受領と同時に、製品データシートの上で貯蔵推薦に従ってください。