CP21R7

製品コードS7954 バッチS795401

化学情報

	Synonyms	CP21	Storage (From the date of receipt)	3 years -20°C powder 1 years -80°C in solvent
	化学式	C₁₉H₁₅N₃O₂
	分子量	317.34	CAS No.	125314-13-8
Solubility (25°C)*	体外	DMSO	63 mg/mL (198.52 mM)
		Ethanol	1 mg/mL warmed with 50ºC water bath (3.15 mM)
		Water	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

溶剤液（一定の濃度）を調合する

生物活性

製品説明	CP21R7 is a potent and selective GSK-3β inhibitor that can potently activate canonical Wnt signalling.

プロトコル(参考用のみ)

参考

[1] Gong L, et al. Bioorg Med Chem Lett. 2010, 20(5):1693-6.

Selleckの高級品が、幾つかの出版された研究調査結果（以下を含む）で使われた：

Generating human artery and vein cells from pluripotent stem cells highlights the arterial tropism of Nipah and Hendra viruses [ Cell, 2022, 185(14):2523-2541.e30]	PubMed: 35738284
Establishment and characterization of immortalized sweat gland myoepithelial cells [ Sci Rep, 2022, 12(1):7]	PubMed: 34997030
Nanoprotein Interaction Atlas Reveals the Transport Pathway of Gold Nanoparticles across Epithelium and Its Association with Wnt/β-Catenin Signaling [ ACS Nano, 2021, 10.1021/acsnano.1c06452]	PubMed: 34672537
Endothelial Progenitor Cells Produced From Human Pluripotent Stem Cells by a Synergistic Combination of Cytokines, Small Compounds, and Serum-Free Medium [ Front Cell Dev Biol, 2020, 15;8:309]	PubMed: 32509776
Gastric-cancer-derived Mesenchymal Stem Cells: A Promising Target for Resveratrol in the Suppression of Gastric Cancer Metastasis [ Hum Cell, 2020, 29]	PubMed: 32350750
Hyperin Controls the Development and Therapy of Gastric Cancer via Regulating Wnt/β-Catenin Signaling [ Cancer Manag Res, 2020, 12:11773-11782]	PubMed: 33235505
Activation of Wnt/β-catenin Pathway Causes Insulin Resistance and Increases Lipogenesis in HepG2 Cells via Regulation of Endoplasmic Reticulum Stress [ Biochem Biophys Res Commun, 2020, 4;526(3):764-771]	PubMed: 32265032
lncRNA-ATB Promotes Stemness Maintenance in Colorectal Cancer by Regulating Transcriptional Activity of the β-Catenin Pathway [ Exp Ther Med, 2020, 19(4):3097-3103]	PubMed: 32256798
Robust differentiation of human pluripotent stem cells into endothelial cells via temporal modulation of ETV2 with modified mRNA [ Sci Adv, 2020, 6(30):eaba7606]	PubMed: 32832668
TIPE1 Impairs Stemness Maintenance in Colorectal Cancer Through Directly Targeting β-catenin. [ Carcinogenesis, 2019, 10.1093/carcin/bgz079]	PubMed: 31111874

長期の保管のために-20°Cの下で製品を保ってください。

人間や獣医の診断であるか治療的な使用のためにでない。

各々の製品のための特定の保管と取扱い情報は、製品データシートの上で示されます。大部分のSelleck製品は、推薦された状況の下で安定です。製品は、推薦された保管温度と異なる温度で、時々出荷されます。長期の保管のために必要とされてそれと異なる温度で、多くの製品は、短期もので安定です。品質を維持するが、夜通しの積荷のために最も経済的な貯蔵状況を用いてあなたの送料を保存する状況の下に、製品が出荷されることを、我々は確実とします。製品の受領と同時に、製品データシートの上で貯蔵推薦に従ってください。