Cytarabine hydrochloride

製品コードS5582 バッチS558201

印刷

化学情報

Chemical Structure Synonyms N/A Storage
(From the date of receipt)		 3 years -20°C powder
化学式

C9H13N3O5.HCl
分子量 279.68 CAS No. 69-74-9
Solubility (25°C)* 体外 DMSO 55 mg/mL (196.65 mM)
 
 
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

溶剤液（一定の濃度）を調合する

生物活性

製品説明 Cytarabine is a pyrimidine nucleoside analog that is used mainly in the treatment of leukemia. It is an antimetabolite antineoplastic agent that inhibits the synthesis of DNA.

プロトコル(参考用のみ)

Selleckの高級品が、幾つかの出版された研究調査結果（以下を含む）で使われた：

Acquired mutations in BAX confer resistance to BH3-mimetic therapy in Acute Myeloid Leukemia [ Blood, 2022, blood.2022016090] PubMed: 36219880
EEF2K silencing inhibits tumour progression through repressing SPP1 and synergises with BET inhibitors in melanoma [ Clin Transl Med, 2022, 12(2):e722] PubMed: 35184394
Establishment and large-scale validation of a three-dimensional tumor model on an array chip for anticancer drug evaluation [ Front Pharmacol, 2022, 13:1032975] PubMed: 36313330
The combination of CUDC-907 and gilteritinib shows promising in vitro and in vivo antileukemic activity against FLT3-ITD AML [ Blood Cancer J, 2021, 11(6):111] PubMed: 34099621
Targeting serine hydroxymethyltransferases 1 and 2 for T-cell acute lymphoblastic leukemia therapy [ Leukemia, 2021, 10.1038/s41375-021-01361-8] PubMed: 34341479
Downregulation of microRNA-9-5p promotes synaptic remodeling in the chronic phase after traumatic brain injury [ Cell Death Dis, 2021, 12(1):9] PubMed: 33414448
Pharmacological inhibition of Carbonic Anhydrase IX and XII to enhance targeting of acute myeloid leukaemia cells under hypoxic conditions [ J Cell Mol Med, 2021, 25(24):11039-11052] PubMed: 34791807
Receptor Activator of NF-κB (RANK) Confers Resistance to Chemotherapy in AML and Associates with Dismal Disease Course [ Cancers (Basel), 2021, 13(23)6122] PubMed: 34885231
Hydroxyurea-induced membrane fluidity decreasing as a characterization of neuronal membrane aging in Alzheimer's disease [ Aging (Albany NY), 2021, 13(9):12817-12832] PubMed: 33972461
High-throughput drug screening reveals Pyrvinium pamoate as effective candidate against pediatric MLL-rearranged acute myeloid leukemia [ Transl Oncol, 2021, 14(5):101048] PubMed: 33667892

長期の保管のために-20°Cの下で製品を保ってください。

人間や獣医の診断であるか治療的な使用のためにでない。

各々の製品のための特定の保管と取扱い情報は、製品データシートの上で示されます。大部分のSelleck製品は、推薦された状況の下で安定です。製品は、推薦された保管温度と異なる温度で、時々出荷されます。長期の保管のために必要とされてそれと異なる温度で、多くの製品は、短期もので安定です。品質を維持するが、夜通しの積荷のために最も経済的な貯蔵状況を用いてあなたの送料を保存する状況の下に、製品が出荷されることを、我々は確実とします。製品の受領と同時に、製品データシートの上で貯蔵推薦に従ってください。