受注:045-509-1970 |
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Synonyms | RS-21592 sodium, Cytovene IV sodium, BW 759 sodium, 2'-Nor-2'-deoxyguanosine sodium | Storage (From the date of receipt) |
3 years -20°C powder 1 years -80°C in solvent |
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化学式 | C9H12N5NaO4 |
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分子量 | 277.21 | CAS No. | 107910-75-8 | |
Solubility (25°C)* | 体外 | Water | 55 mg/mL (198.4 mM) | |
DMSO | Insoluble | |||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
製品説明 | Ganciclovir Sodium (RS-21592, Cytovene IV, BW 759, 2'-Nor-2'-deoxyguanosine) is the sodium salt form of ganciclovir, a synthetic, antiviral, purine nucleoside analog with antiviral activity, especially against cytomegalovirus (CMV). |
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in vitro | Ganciclovir Sodium (RS-21592, Cytovene IV, BW 759, 2'-Nor-2'-deoxyguanosine) is the sodium salt form of ganciclovir, a synthetic, antiviral, purine nucleoside analog with antiviral activity, especially against cytomegalovirus (CMV). |
細胞アッセイ | 細胞株 | TM cells |
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濃度 | 0, 10, 100 μM | |
反応時間 | 1, 3, 5 and 7 days | |
実験の流れ | Cells were treated with indicated concentration of drug for several days. |
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動物実験 | 動物モデル | C57BL/6 mice |
投薬量 | 30 mg/kg | |
投与方法 | i.p. |
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A novel inducible haematopoietic cell-depleting mouse model for chimeric complementation of blood cells [ Cell Prolif, 2023, 56(5):e13472] | PubMed: 37199017 |
Tumor perivascular cell-derived extracellular vesicles promote angiogenesis via the Gas6/Axl pathway [ Cancer Lett, 2022, 524:131-143] | PubMed: 34678434 |
Senescent hepatic stellate cells promote liver regeneration through IL-6 and ligands of CXCR2 [ JCI Insight, 2022, 7(14)e158207] | PubMed: 35708907 |
Evaluation of the stability and intratumoral delivery of foreign transgenes encoded by an oncolytic Foamy Virus vector [ Cancer Gene Ther, 2022, 10.1038/s41417-022-00431-y] | PubMed: 35145270 |
Safety, efficacy and delivery of multiple nucleoside analogs via drug encapsulated carbon (DECON) based sustained drug release platform [ Eur J Pharm Biopharm, 2022, S0939-6411(22)00047-9] | PubMed: 35314347 |
6-Thioguanine Inhibits Herpes Simplex Virus 1 Infection of Eyes [ Microbiol Spectr, 2021, 9(3):e0064621] | PubMed: 34730435 |
Targeting Tumor Neoangiogenesis via Targeted Adenoviral Vector to Achieve Effective Cancer Gene Therapy for Disseminated Neoplastic Disease [ Mol Cancer Ther, 2020, 19(3):966-971] | PubMed: 31907220 |
Standalone or combinatorial phenylbutyrate therapy shows excellent antiviral activity and mimics CREB3 silencing [ Sci Adv, 2020, 6(49)eabd9443] | PubMed: 33277262 |
[ Neuroendocrinology, 2019, ] | PubMed: 31280274 |
The effects of losartan on cytomegalovirus infection in human trabecular meshwork cells [ PLoS One, 2019, 14(6):e0218471] | PubMed: 31216320 |
長期の保管のために-20°Cの下で製品を保ってください。
人間や獣医の診断であるか治療的な使用のためにでない。
各々の製品のための特定の保管と取扱い情報は、製品データシートの上で示されます。大部分のSelleck製品は、推薦された状況の下で安定です。製品は、推薦された保管温度と異なる温度で、時々出荷されます。長期の保管のために必要とされてそれと異なる温度で、多くの製品は、短期もので安定です。品質を維持するが、夜通しの積荷のために最も経済的な貯蔵状況を用いてあなたの送料を保存する状況の下に、製品が出荷されることを、我々は確実とします。製品の受領と同時に、製品データシートの上で貯蔵推薦に従ってください。