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Synonyms | (+)-Genipin | Storage (From the date of receipt) |
3 years -20°C powder 1 years -80°C in solvent |
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化学式 | C11H14O5 |
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分子量 | 226.23 | CAS No. | 6902-77-8 | |
Solubility (25°C)* | 体外 | DMSO | 45 mg/mL (198.91 mM) | |
Ethanol | 45 mg/mL (198.91 mM) | |||
Water | 1 mg/mL (4.42 mM) | |||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
製品説明 | Genipin((+)-Genipin) is an active aglycone derived from an iridoid glycoside called geniposide, which is found in the fruit of Gardenia jasminoides Ellis. |
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Data from [Data independently produced by , , Sci Rep, 2015, 5:17935]
Genipin relieves diabetic retinopathy by down-regulation of advanced glycation end products via the mitochondrial metabolism related signaling pathway [ World J Diabetes, 2023, 10.4239/wjd.v14.i9.1349] | PubMed: 37771331 |
The neuroprotective mechanism of lithium after ischaemic stroke [ Commun Biol, 2022, 5(1):105] | PubMed: 35115638 |
Malvidin alleviates mitochondrial dysfunction and ROS accumulation through activating AMPK-α/UCP2 axis, thereby resisting inflammation and apoptosis in SAE mice [ Front Pharmacol, 2022, 13:1038802] | PubMed: 36699054 |
Signal transducer and transcriptional activation 1 protects against pressure overload-induced cardiac hypertrophy [ FASEB J, 2021, 35(1):e21240] | PubMed: 33377257 |
Irisin reverses intestinal epithelial barrier dysfunction during intestinal injury via binding to the integrin αVβ5 receptor. [ J Cell Mol Med, 2020, 24(1):996-1009] | PubMed: 31701659 |
Genipin inhibits the invasion and migration of colon cancer cells by the suppression of HIF-1α accumulation and VEGF expression [ Food Chem Toxicol, 2018, 116(Pt B):70-76] | PubMed: 29630948 |
Genipin inhibits NLRP3 and NLRC4 inflammasome activation via autophagy suppression. [Yu SX, et al. Sci Rep, 2015, 5:17935] | PubMed: 26659006 |
長期の保管のために-20°Cの下で製品を保ってください。
人間や獣医の診断であるか治療的な使用のためにでない。
各々の製品のための特定の保管と取扱い情報は、製品データシートの上で示されます。大部分のSelleck製品は、推薦された状況の下で安定です。製品は、推薦された保管温度と異なる温度で、時々出荷されます。長期の保管のために必要とされてそれと異なる温度で、多くの製品は、短期もので安定です。品質を維持するが、夜通しの積荷のために最も経済的な貯蔵状況を用いてあなたの送料を保存する状況の下に、製品が出荷されることを、我々は確実とします。製品の受領と同時に、製品データシートの上で貯蔵推薦に従ってください。