Gentamicin Sulfate

製品コードS4030 バッチS403003

化学情報

	Synonyms	NSC-82261, SCH9724	Storage (From the date of receipt)	3 years -20°C powder 1 years -80°C in solvent
	化学式	H₂SO₄.xUnspecified
	分子量		CAS No.	1405-41-0
Solubility (25°C)*	体外	Water	100 mg/mL
		DMSO	Insoluble
		Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

生物活性

製品説明	Gentamycin Sulfate (NSC-82261, SCH9724) is a broad-spectrum, aminoglycoside antibiotic used for cell culture which inhibits protein synthesis in sensitive organisms.
in vitro	Gentamycin Sulfate is a complex of three different closely related aminoglycoside sulfates, Gentamicins c1, c1a and c2, obtained from Micromonospora purpurea and related species. ^[1] They are broad-spectrum antibiotics, but may cause ear and kidney damage. Gentamycin Sulfate is reported to have activity against gram-negative bacteria, Pseudomonas aeruginosa, gram-positive Staphylococcus aureus and some mycoplasmas. Reported to have low toxicity to mammalian cells and viruses at certain concentrations, useful for long-term tissue culture studies with viruses. ^[2] Gentamicin acts by binding to the 30S subunit of the bacterial ribosome leading to inhibition of protein synthesis and death in susceptible bacteria. ^[3]

製品説明

Gentamycin Sulfate (NSC-82261, SCH9724) is a broad-spectrum, aminoglycoside antibiotic used for cell culture which inhibits protein synthesis in sensitive organisms.

in vitro

Gentamycin Sulfate is a complex of three different closely related aminoglycoside sulfates, Gentamicins c1, c1a and c2, obtained from Micromonospora purpurea and related species. ^[1] They are broad-spectrum antibiotics, but may cause ear and kidney damage. Gentamycin Sulfate is reported to have activity against gram-negative bacteria, Pseudomonas aeruginosa, gram-positive Staphylococcus aureus and some mycoplasmas. Reported to have low toxicity to mammalian cells and viruses at certain concentrations, useful for long-term tissue culture studies with viruses. ^[2] Gentamicin acts by binding to the 30S subunit of the bacterial ribosome leading to inhibition of protein synthesis and death in susceptible bacteria. ^[3]

プロトコル(参考用のみ)

参考

Selleckの高級品が、幾つかの出版された研究調査結果（以下を含む）で使われた：

Itaconate is a lysosomal inducer that promotes antibacterial innate immunity [ Mol Cell, 2022, S1097-2765(22)00443-9]	PubMed: 35662396
Präklinische ex vivo-Effekte von CFTR-Modulatoren an humanen Rektumbiopsien zur Medikamentenentwicklung bei Mukoviszidose [ Universitätsmedizin Berlin, 2021, 10.17169/refubium-29871]	PubMed: None
Identification of Required Host Factors for SARS-CoV-2 Infection in Human Cells [ Cell, 2020, S0092-8674(20)31394-5]	PubMed: 33147445

長期の保管のために-20°Cの下で製品を保ってください。

人間や獣医の診断であるか治療的な使用のためにでない。

各々の製品のための特定の保管と取扱い情報は、製品データシートの上で示されます。大部分のSelleck製品は、推薦された状況の下で安定です。製品は、推薦された保管温度と異なる温度で、時々出荷されます。長期の保管のために必要とされてそれと異なる温度で、多くの製品は、短期もので安定です。品質を維持するが、夜通しの積荷のために最も経済的な貯蔵状況を用いてあなたの送料を保存する状況の下に、製品が出荷されることを、我々は確実とします。製品の受領と同時に、製品データシートの上で貯蔵推薦に従ってください。