Iron sucrose

製品コードS3729 バッチS372901

化学情報

	Synonyms	Iron saccharate, Sucroferric oxyhydroxide	Storage (From the date of receipt)	3 years -20°C powder 1 years -80°C in solvent
	化学式	C₁₈H₂₄Fe₂O₂₄
	分子量	736.06	CAS No.	8047-67-4
Solubility (25°C)*	体外	DMSO	100 mg/mL (135.85 mM)
		Water	100 mg/mL (135.85 mM)
		Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

溶剤液（一定の濃度）を調合する

生物活性

製品説明	Iron sucrose (Iron saccharate, Sucroferric oxyhydroxide) is an intravenously administered iron product indicated in the treatment of iron deficiency anemia.
in vitro	Iron sucrose (0.01 mg/mL) used as an additive to culture medium for 24 h was cytotoxic to human peritoneal mesothelial cells in in vitro culture as reflected by its effect on the cells' growth, viability and synthesis of IL-6; all these effects were dosedependent. At higher, concentrations cytotoxic effects of iron sucrose appeared. Toxic effect of iron towards the mesothelial cells may be linked to increased production of free radicals. Iron sucrose enters into the cytosol of the mesothelial cells, where it is probably transported in a process of endocytosis^[1].

製品説明

Iron sucrose (Iron saccharate, Sucroferric oxyhydroxide) is an intravenously administered iron product indicated in the treatment of iron deficiency anemia.

in vitro

Iron sucrose (0.01 mg/mL) used as an additive to culture medium for 24 h was cytotoxic to human peritoneal mesothelial cells in in vitro culture as reflected by its effect on the cells' growth, viability and synthesis of IL-6; all these effects were dosedependent. At higher, concentrations cytotoxic effects of iron sucrose appeared. Toxic effect of iron towards the mesothelial cells may be linked to increased production of free radicals. Iron sucrose enters into the cytosol of the mesothelial cells, where it is probably transported in a process of endocytosis^[1].

プロトコル(参考用のみ)

細胞アッセイ	細胞株	human peritoneal mesothelial cells.
	濃度	0.01 mg/mL
	反応時間	24 h
	実験の流れ	--

参考

[1] Breborowicz M, et al. Eur J Clin Invest. 2003, 33(12):1038-44.

長期の保管のために-20°Cの下で製品を保ってください。

人間や獣医の診断であるか治療的な使用のためにでない。

各々の製品のための特定の保管と取扱い情報は、製品データシートの上で示されます。大部分のSelleck製品は、推薦された状況の下で安定です。製品は、推薦された保管温度と異なる温度で、時々出荷されます。長期の保管のために必要とされてそれと異なる温度で、多くの製品は、短期もので安定です。品質を維持するが、夜通しの積荷のために最も経済的な貯蔵状況を用いてあなたの送料を保存する状況の下に、製品が出荷されることを、我々は確実とします。製品の受領と同時に、製品データシートの上で貯蔵推薦に従ってください。