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Synonyms | FK 463, Mycamine | Storage (From the date of receipt) |
3 years -20°C(in the dark) powder | |
化学式 | C56H70N9NaO23S |
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分子量 | 1292.26 | CAS No. | 208538-73-2 | |
Solubility (25°C)* | 体外 | DMSO | 100 mg/mL warmed with 50ºC water bath (77.38 mM) | |
Water | 100 mg/mL (77.38 mM) | |||
Ethanol | Insoluble | |||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
製品説明 | Micafungin Sodium is an inhibitor of 1, 3-beta-D-glucan synthesis, used as an antifungal drug. |
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in vitro | Micafungin is an antifungal agent that does not inhibit bacteria. Although micafungin does not inhibit the bacteria directly, it does promote the survival of G. mellonella[1]. Micafungin inhibits biofilm formation by impeding 1,3-β-D-glucan synthesis in Candida albicans[2]. |
細胞アッセイ | 細胞株 | bactrial cells |
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濃度 | 10 mg/ml | |
反応時間 | -- | |
実験の流れ | -- |
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動物実験 | 動物モデル | CD1 mice |
投薬量 | 5 mg/kg/day | |
投与方法 | i.p. |
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Data from [Data independently produced by , , Cell Physiol Biochem, 2016, 584-95]
Data from [Data independently produced by , , Virol J, 2016, 13(1):99.]
Data from [Data independently produced by , , Antiviral Res, 2018, 159:134-142]
Upc2-mediated mechanisms of azole resistance in Candida auris [ Microbiol Spectr, 2024, e0352623.] | PubMed: 38206035 |
Antiviral activity and mechanism of the antifungal drug, anidulafungin, suggesting its potential to promote treatment of viral diseases [ BMC Med, 2022, 20(1):359] | PubMed: 36266654 |
Synergistic in-vitro antiviral effects of combination treatment using anidulafungin and T-1105 against Zika virus infection [ Antiviral Res, 2021, S0166-3542(21)00178-9] | PubMed: 34648875 |
Micafungin Inhibits Dengue Virus Infection through the Disruption of Virus Binding, Entry, and Stability [ Pharmaceuticals (Basel), 2021, 14(4)338] | PubMed: 33917182 |
Assessment of the In Vitro and In Vivo Antifungal Activity of NSC319726 against Candida auris [ Microbiol Spectr, 2021, 9(3):e0139521] | PubMed: 34730380 |
Evaluation of artemisinin derivative artemether as a fluconazole potentiator through inhibition of Pdr5 [ Bioorg Med Chem, 2021, 44:116293] | PubMed: 34243044 |
Inhibiting Fungal Echinocandin Resistance by Small-Molecule Disruption of Geranylgeranyltransferase Type I Activity. [ Antimicrob Agents Chemother, 2020, 64(2)] | PubMed: 31791942 |
Molecular Identification and Antifungal Susceptibility Profile of Yeast From Vulvovaginal Candidiasis [ BMC Infect Dis, 2020, 19;20(1):287] | PubMed: 32393342 |
The fungal cell wall as a target for the development of new antifungal therapies. [ Biotechnol Adv, 2019, 37(6):107352] | PubMed: 30797093 |
Micafungin is a novel anti-viral agent of chikungunya virus through multiple mechanisms [Ho YJ, et al. Antiviral Res, 2018, 159:134-142] | PubMed: 30300716 |
長期の保管のために-20°Cの下で製品を保ってください。
人間や獣医の診断であるか治療的な使用のためにでない。
各々の製品のための特定の保管と取扱い情報は、製品データシートの上で示されます。大部分のSelleck製品は、推薦された状況の下で安定です。製品は、推薦された保管温度と異なる温度で、時々出荷されます。長期の保管のために必要とされてそれと異なる温度で、多くの製品は、短期もので安定です。品質を維持するが、夜通しの積荷のために最も経済的な貯蔵状況を用いてあなたの送料を保存する状況の下に、製品が出荷されることを、我々は確実とします。製品の受領と同時に、製品データシートの上で貯蔵推薦に従ってください。