受注:045-509-1970 |
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製品コード:A2008 Batch: A200803
Pertuzumab, a humanized monoclonal antibody and the first in the class of agents called the HER2 dimerization inhibitors, impairs the ability of HER2 to bind to other members of the HER family, MW: 148 KD.
CAS No. | 380610-27-5 |
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Formulation | PBS buffer, pH 7.2 |
Isotype | Human IgG1 |
Source | CHO cells |
Storage (From the date of receipt) |
Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles |
Shipping | Shipped under low temperature conditions |
Purity | 98.61% |
Protein concentration | 5 mg/ml |
Endotoxin Level | <1 EU/mg |
Multi-Targeting Anticancer Activity of a New 4-Thiazolidinone Derivative with Anti-HER2 Antibodies in Human AGS Gastric Cancer Cells [ Int J Mol Sci, 2023, 24(7)6791] | PubMed: 37047765 |
The effect of the alpha-specific PI3K inhibitor alpelisib combined with anti-HER2 therapy in HER2+/PIK3CA mutant breast cancer [ Front Oncol, 2023, 13:1108242] | PubMed: 37469415 |
Establishment and large-scale validation of a three-dimensional tumor model on an array chip for anticancer drug evaluation [ Front Pharmacol, 2022, 13:1032975] | PubMed: 36313330 |
Optical biosensor based on weak value amplification for the high sensitivity detection of Pertuzumab in combination with Trastuzumab binding to the extracellular domain of HER2 [ Opt Express, 2022, 30(20):36839-36848] | PubMed: 36258605 |
Anti-HER2 monoclonal antibodies intensify the susceptibility of human gastric cancer cells to etoposide by promoting apoptosis, but not autophagy [ PLoS One, 2021, 16(8):e0255585] | PubMed: 34437575 |
A common MET polymorphism harnesses HER2 signaling to drive aggressive squamous cell carcinoma [ Nat Commun, 2020, 11(1):1556] | PubMed: 32214092 |
WEE1 inhibitor, AZD1775, overcomes trastuzumab resistance by targeting cancer stem-like properties in HER2-positive breast cancer. [ Cancer Lett, 2020, 472:119-131] | PubMed: 31866466 |
人間や獣医の診断であるか治療的な使用のためにでない。