Rituximab (anti-CD20)

製品コード：A2009         Batch: A200907

印刷

Rituximab is a chimeric anti-CD20 mAb that binds the CD20 antigen on B cells with a binding affinity of 5 nM, MW: 143.86 KD.

製品説明

CAS No. 174722-31-7
Formulation PBS buffer, pH 7.2
Isotype Human IgG1
Source CHO cells
Storage
(From the date of receipt)		 Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles
Shipping Shipped under low temperature conditions
Purity 99%
Protein concentration 5.8 mg/ml
Endotoxin Level ＜1EU/mg

Selleckの高級品が、幾つかの出版された研究調査結果（以下を含む）で使われた：

Distinct CD16a features on human NK cells observed by flow cytometry correlate with increased ADCC [ Sci Rep, 2024, 14(1):7938] PubMed: 38575779
Noninvasive PET imaging of tumor PD-L1 expression with 64Cu-labeled Durvalumab [ Am J Nucl Med Mol Imaging, 2024, 14(1):31-40] PubMed: 38500749
Daratumumab induces cell-mediated cytotoxicity of primary effusion lymphoma and is active against refractory disease [ Oncoimmunology, 2023, 12(1):2163784] PubMed: 36632565
Development and implementation of natural killer cell simultaneous ADCC and direct killing assay [ Heliyon, 2023, 9(12):e22991] PubMed: 38125417
Rheumatoid factor IgM autoantibodies control IgG homeostasis [ Front Immunol, 2022, 13:1016263] PubMed: 36341420
Beta-Lapachone Attenuates BMSC-Mediated Neuroblastoma Malignant Transformation by Inhibiting Gal-3/Gal-3BP/IL6 Axis [ J Pharmacol Exp Ther, 2022, 381(1):12-21] PubMed: 35078863
A versatile platform for the tumor-targeted delivery of immune checkpoint-blocking immunoglobin G [ J Control Release, 2021, 340:243-258] PubMed: 34752799
Study of the antilymphoma activity of pracinostat reveals different sensitivities of DLBCL cells to HDAC inhibitors [ Blood Adv, 2021, 5(10):2467-2480] PubMed: 33999145
Salt-dependent passive adsorption of IgG1κ-type monoclonal antibodies on hydrophobic microparticles [ Biophys Chem, 2021, 275:106609] PubMed: 33975078
Tumor-Targeting Liposomes with Transient Holes Allowing Intact Rituximab Internally [ Biomacromolecules, 2020, 22(2):723-731] PubMed: 33280388

人間や獣医の診断であるか治療的な使用のためにでない。