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受注：045-509-1970 |
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Trastuzumab (anti-HER2)
製品コード：A2007 Batch: A200706
Trastuzumab is a humanized, recombinant monoclonal antibody that binds to the extracellular domain of HER2, MW:145.53 KD.
製品説明
| CAS No. | 180288-69-1 |
|---|---|
| Formulation | PBS buffer, pH 7.2 |
| Isotype | Human IgG1 |
| Source | CHO cells |
| Storage (From the date of receipt) |
Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles |
| Shipping | Shipped under low temperature conditions |
| Purity | 99.84% |
| Protein concentration | 3.27 mg/ml |
| Endotoxin Level | <1 EU/mg |
カスタマーフィードバック
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Selleckの高級品が、幾つかの出版された研究調査結果（以下を含む）で使われた：
| Identification of a novel potent CDK inhibitor degrading cyclinK with a superb activity to reverse trastuzumab-resistance in HER2-positive breast cancer in vivo [ Eur J Med Chem, 2024, 264:116014] | PubMed: 38061230 |
| Neddylation of HER2 Inhibits its Protein Degradation and promotes Breast Cancer Progression [ Int J Biol Sci, 2023, 19(2):377-392] | PubMed: 36632463 |
| Irreversible HER2 inhibitors overcome resistance to the RSL3 ferroptosis inducer in non-HER2 amplified luminal breast cancer [ Cell Death Dis, 2023, 14(8):532] | PubMed: 37596261 |
| Detecting Disruption of HER2 Membrane Protein Organization in Cell Membranes with Nanoscale Precision [ ACS Sens, 2023, 10.1021/acssensors.3c01437] | PubMed: 37955934 |
| T lymphocytes expressing the switchable chimeric Fc receptor CD64 exhibit augmented persistence and antitumor activity [ Cell Rep, 2023, 42(7):112797] | PubMed: 37436890 |
| Engineering choroid plexus-on-a-chip with oscillatory flow for modeling brain metastasis [ Mater Today Bio, 2023, 22:100773] | PubMed: 37664794 |
| Multi-Targeting Anticancer Activity of a New 4-Thiazolidinone Derivative with Anti-HER2 Antibodies in Human AGS Gastric Cancer Cells [ Int J Mol Sci, 2023, 24(7)6791] | PubMed: 37047765 |
| The effect of the alpha-specific PI3K inhibitor alpelisib combined with anti-HER2 therapy in HER2+/PIK3CA mutant breast cancer [ Front Oncol, 2023, 13:1108242] | PubMed: 37469415 |
| Immune suppressive signaling regulated by latent transforming growth factor beta binding protein 1 promotes metastasis in cervical cancer [ Braz J Med Biol Res, 2023, 55:e12206] | PubMed: 36629522 |
| Generation and Integrated Analysis of Advanced Patient-Derived Orthoxenograft Models (PDOX) for the Rational Assessment of Targeted Therapies in Endometrial Cancer [ Adv Sci (Weinh), 2022, e2204211] | PubMed: 36373729 |
人間や獣医の診断であるか治療的な使用のためにでない。