Troxipide

製品コードS4128 バッチS412801

化学情報

	Synonyms	KU 54	Storage (From the date of receipt)	3 years -20°C powder 1 years -80°C in solvent
	化学式	C₁₅H₂₂N₂O₄
	分子量	294.35	CAS No.	30751-05-4
Solubility (25°C)*	体外	DMSO	18 mg/mL (61.15 mM)
		Ethanol	3 mg/mL (10.19 mM)
		Water	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

溶剤液（一定の濃度）を調合する

生物活性

製品説明	Troxipide(KU 54) is a novel systemic non-antisecretory gastric cytoprotective agent with anti-ulcer, anti-inflammatory and mucus secreting properties irrespective of pH of stomach or duodenum.
in vitro	Troxipide is a novel antiulcer compound which has inhibitory effects on human neutrophil migration and activation induced by various stimulants.^[1] Troxipide is a new gastric cytoprotective agent, which neither inhibits acid secretion nor has acid neutralizing activity, but has been clinically proven to heal gastritis and gastric ulcers. Troxipide is shown to inhibit neutrophil mediated inflammation and oxidative stress in addition to improving the gastric mucus composition and output. Furthermore, it is found to increase the secretion of cytoprotective prostaglandins. The gastric mucosal metabolism and blood flow are also enhanced by Troxipide. ^[2]

製品説明

Troxipide(KU 54) is a novel systemic non-antisecretory gastric cytoprotective agent with anti-ulcer, anti-inflammatory and mucus secreting properties irrespective of pH of stomach or duodenum.

in vitro

Troxipide is a novel antiulcer compound which has inhibitory effects on human neutrophil migration and activation induced by various stimulants.^[1] Troxipide is a new gastric cytoprotective agent, which neither inhibits acid secretion nor has acid neutralizing activity, but has been clinically proven to heal gastritis and gastric ulcers. Troxipide is shown to inhibit neutrophil mediated inflammation and oxidative stress in addition to improving the gastric mucus composition and output. Furthermore, it is found to increase the secretion of cytoprotective prostaglandins. The gastric mucosal metabolism and blood flow are also enhanced by Troxipide. ^[2]

プロトコル(参考用のみ)

参考

Selleckの高級品が、幾つかの出版された研究調査結果（以下を含む）で使われた：

3D imaging analysis on an organoid-based platform guides personalized treatment in pancreatic ductal adenocarcinoma [ J Clin Invest, 2022, 132(24)e151604]	PubMed: 36282600

3D imaging analysis on an organoid-based platform guides personalized treatment in pancreatic ductal adenocarcinoma [ J Clin Invest, 2022, 132(24)e151604]

PubMed: 36282600

長期の保管のために-20°Cの下で製品を保ってください。

人間や獣医の診断であるか治療的な使用のためにでない。

各々の製品のための特定の保管と取扱い情報は、製品データシートの上で示されます。大部分のSelleck製品は、推薦された状況の下で安定です。製品は、推薦された保管温度と異なる温度で、時々出荷されます。長期の保管のために必要とされてそれと異なる温度で、多くの製品は、短期もので安定です。品質を維持するが、夜通しの積荷のために最も経済的な貯蔵状況を用いてあなたの送料を保存する状況の下に、製品が出荷されることを、我々は確実とします。製品の受領と同時に、製品データシートの上で貯蔵推薦に従ってください。