Ephrin receptor

Ephrin receptor製品

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  • Ephrin receptor阻害剤 (5)
  • 新製品
製品コード 製品名称 製品説明 文献中Selleckの製品使用例 お客様のフィードバック
S2202 NVP-BHG712 NVP-BHG712 is a specific EphB4 inhibitor with ED50 of 25 nM that discriminates between VEGFR and EphB4 inhibition; also shows activity against c-Raf, c-Src and c-Abl with IC50 of 0.395 μM, 1.266 μM and 1.667 μM, respectively.
Cell Rep, 2022, 41(11):111827
Oncogene, 2022, 10.1038/s41388-022-02519-z
Cell Rep, 2021, 35(1):108940
S8573 Sitravatinib (MGCD516) Sitravatinib (MGCD516, MG-516) is a novel small molecule inhibitor targeting multiple RTKs involved in driving sarcoma cell growth, including c-Kit, PDGFRβ, PDGFRα, c-Met, and Axl.
JCI Insight, 2022, e148717
Cancers (Basel), 2021, 13(21)5474
Cancers (Basel), 2020, 12(1)
S0256 Ehp-inhibitor-1 Ehp-inhibitor-1 (Ehp inhibitor 2) is an Eph family tyrosine kinase inhibitor that targets Eph receptors.
E2835 NVP-BHG712 isomer NVP-BHG712 isomer, a regioisomer of NVP-BHG712, shows conserved non-bonded binding to EphA2 and EphB4.
E0614 AWL-II-38.3 AWL-II-38.3 is a potent Ephrin type-A receptor 3 (EphA3) kinase inhibitor.
S6515 ALW II-41-27 ALW II-41-27 (compound 7) is a potent inhibitor of Eph receptor tyrosine kinase with Kd of 12 nM for EphA2.
S2202 NVP-BHG712 NVP-BHG712 is a specific EphB4 inhibitor with ED50 of 25 nM that discriminates between VEGFR and EphB4 inhibition; also shows activity against c-Raf, c-Src and c-Abl with IC50 of 0.395 μM, 1.266 μM and 1.667 μM, respectively.
Cell Rep, 2022, 41(11):111827
Oncogene, 2022, 10.1038/s41388-022-02519-z
Cell Rep, 2021, 35(1):108940
S8573 Sitravatinib (MGCD516) Sitravatinib (MGCD516, MG-516) is a novel small molecule inhibitor targeting multiple RTKs involved in driving sarcoma cell growth, including c-Kit, PDGFRβ, PDGFRα, c-Met, and Axl.
JCI Insight, 2022, e148717
Cancers (Basel), 2021, 13(21)5474
Cancers (Basel), 2020, 12(1)
S0256 Ehp-inhibitor-1 Ehp-inhibitor-1 (Ehp inhibitor 2) is an Eph family tyrosine kinase inhibitor that targets Eph receptors.
E0614 AWL-II-38.3 AWL-II-38.3 is a potent Ephrin type-A receptor 3 (EphA3) kinase inhibitor.
S6515 ALW II-41-27 ALW II-41-27 (compound 7) is a potent inhibitor of Eph receptor tyrosine kinase with Kd of 12 nM for EphA2.

Ephrin receptor阻害剤の選択性比較

Ephrin receptorシグナル伝達経路

Ephrin receptorシグナル伝達経路
Tags: Ephrin receptor inhibitor|Ephrin receptor agonist|Ephrin receptor activator|Ephrin receptor inducer|Ephrin receptor antagonist|Ephrin receptor signaling pathway|Ephrin receptor assay kit