ヒストンアセチルトランスフェラーゼ

シグナル伝達経路

研究分野

  • 阻害剤の選択性比較
  • 溶解度
カタログ番号 製品カタログ 溶解度(25°C)
DMSO アルコール
S7152 C646 <1 mg/mL 13 mg/mL <1 mg/mL
S1848 Curcumin <1 mg/mL 73 mg/mL <1 mg/mL
S7582 Anacardic Acid <1 mg/mL 69 mg/mL 69 mg/mL
S7641 Remodelin <1 mg/mL 72 mg/mL <1 mg/mL
S7476 MG149 <1 mg/mL 68 mg/mL 68 mg/mL
製品コード 製品説明 文献中の使用例 お客様のフィードバック
S7152

C646

C646 is an inhibitor for histone acetyltransferase, and inhibits p300 with a Ki of 400 nM in a cell-free assay. Preferentially selective for p300 versus other acetyltransferases.

S1848

Curcumin

Curcumin is the principal curcuminoid of the popular Indian spice turmeric, which is a member of the ginger family (Zingiberaceae). It is an inhibitor of p300 histone acetylatransferase(IC50~25 μM) and Histone deacetylase; activates Nrf2 pathway and supresses the activation of transcription factor NF-κB.

S7582

Anacardic Acid

Anacardic Acid is a potent inhibitor of p300 and p300/CBP-associated factor histone acetyltranferases, which also has antibacterial activity, antimicrobial activity, prostaglandin synthase inhibition, and tyrosinase and lipoxygenase inhibition.

S7641

Remodelin

Remodelin is a potent acetyl-transferase NAT10 inhibitor.

S7476

MG149

MG149 is a potent histone acetyltransferase inhibitor with IC50 of 74 μM and 47 μM for Tip60 and MOF,respectively.