ホームページ Neuronal Signaling -GPCR & G Protein Dopamine Receptor DAT 選択性 阻害剤 | モジュレータ
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DAT 選択性 阻害剤 | モジュレータ

製品コード 製品名 製品説明 Selective / Pan IC50 / Ki
S6301 MPP+ iodide MPP+ iodide (N-Methyl-4-Phenylpyridinium Iodide), the metabolite of a neurotoxin MPTP, causes symptom of Parkinson's disease (PD) in animal models by selectively destroying dopaminergic neurons in substantia nigra. MPP+ induces autophagic cell death in SH-SY5Y cells. MPP+ induces dopamine transporter (DAT) externalization in dopaminergic (DA) neurons, but internalization of serotonin transporter (SERT) in serotonergic (5-HT) neurons. Selective
S3163 Benztropine mesylate Benztropine(Cogentin mesylate, Benztropine methanesulfonate) is a dopamine transporter (DAT) inhibitor with IC50 of 118 nM. Selective DAT, IC50: 118 nM