• PAK1
  • PAK3
  • PAK2
  • PAK4
  • PAK5
  • PAK6

PAK3 阻害剤

製品コード 製品名 製品説明 Selective / Pan IC50 / Ki
S7271 FRAX597 FRAX597 is a potent, ATP-competitive inhibitor of group I PAKs with IC50 of 8 nM, 13 nM, and 19 nM for PAK1, PAK2, and PAK3, respectively. Pan PAK3, IC50: 19 nM
S7807 FRAX486 FRAX486 is a potent p21-activated kinase (PAK) inhibitor with IC50 values of 14, 33, 39 and 575 nM for PAK1, PAK2, PAK3 and PAK4 respectively. Pan PAK3, IC50: 39 nM
S7094 PF-3758309 PF-03758309 (PF-03758309) is a potent, ATP-competitive, pyrrolopyrazole inhibitor of PAK4 with Kd of 2.7 nM. PF-3758309 is antiproliferative and induces apoptosis in a HCT116 tumor model. Pan PAK3, IC50: 99 nM