1-Triacontanol

製品コードS5172 バッチS517201

化学情報

	Synonyms	n-Triacontanol, Melissyl alcohol, Myricyl alcohol	Storage (From the date of receipt)	3 years -20°C powder 1 years -80°C in solvent
	化学式	C₃₀H₆₂O
	分子量	438.81	CAS No.	593-50-0
Solubility (25°C)*	体外	4-Methylpyridine	10 mg/mL warmed with 50ºC water bath (22.78 mM)
		Ethanol	1 mg/mL (2.27 mM)
		DMSO	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

溶剤液（一定の濃度）を調合する

生物活性

製品説明	1-Triacontanol (n-Triacontanol, Melissyl alcohol, Myricyl alcohol) is a fatty alcohol found in plant cuticle waxes and in beeswax. It is a growth stimulant for many plants, most notably roses.
in vivo	The area under concentration-time curve AUC_{0-6 h and AUC_0-∞ for 1-Triacontanol (TA) at 60 mg/kg are 87.737±13.574 and 93.617±17.62, respectively. The mean residence time is 3.25 ± 0.17 h. In addition, the elimination half-lives (t_1/2) are (2.37±1.23, 1.27±0.49, 2.07±0.93) h after single oral administration of 30, 60 and 120 mg/kg of TA. After oral administration, TA is extensively distributed in stomach and intestine. The majority of TA excrete via feces, and its accumulative excretion ratio during the period of 72 h is 26.68 ± 7.14%, but only 0.0023 ± 0.0015% and 0.0027 ± 0.0006% for urines and bile, respectively. The absolute bioavailability (F, %) of TA is about 2.0%. TA is regarded as a promising anti-cancer compound with less or no toxicity. Due to low bioavailability and undesirable half-life^[1].}

製品説明

1-Triacontanol (n-Triacontanol, Melissyl alcohol, Myricyl alcohol) is a fatty alcohol found in plant cuticle waxes and in beeswax. It is a growth stimulant for many plants, most notably roses.

in vivo

The area under concentration-time curve AUC_{0-6 h and AUC_0-∞ for 1-Triacontanol (TA) at 60 mg/kg are 87.737±13.574 and 93.617±17.62, respectively. The mean residence time is 3.25 ± 0.17 h. In addition, the elimination half-lives (t_1/2) are (2.37±1.23, 1.27±0.49, 2.07±0.93) h after single oral administration of 30, 60 and 120 mg/kg of TA. After oral administration, TA is extensively distributed in stomach and intestine. The majority of TA excrete via feces, and its accumulative excretion ratio during the period of 72 h is 26.68 ± 7.14%, but only 0.0023 ± 0.0015% and 0.0027 ± 0.0006% for urines and bile, respectively. The absolute bioavailability (F, %) of TA is about 2.0%. TA is regarded as a promising anti-cancer compound with less or no toxicity. Due to low bioavailability and undesirable half-life^[1].}

プロトコル(参考用のみ)

動物実験	動物モデル	Sprague-Dawley rats
	投薬量	60 mg/kg
	投与方法	oral administration

参考

[1] Wang C, et al. Xenobiotica. 2015, 45(1):71-8.

長期の保管のために-20°Cの下で製品を保ってください。

人間や獣医の診断であるか治療的な使用のためにでない。

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