Dipyridamole

製品コードS1895 バッチS189502

印刷

化学情報

Chemical Structure Synonyms NSC-515776 Storage
(From the date of receipt)		 3 years -20°C powder
1 years -80°C in solvent
化学式

C24H40N8O4
分子量 504.63 CAS No. 58-32-2
Solubility (25°C)* 体外 DMSO 100 mg/mL (198.16 mM)
Ethanol 50 mg/mL (99.08 mM)
Water Insoluble
体内 （毎回新しく調製した物を用意してください）
Homogeneous suspension
CMC-NA
≥5mg/ml Taking the 1 mL working solution as an example, add 5 mg of this product to 1 ml of CMC-Na solution, mix evenly to obtain a homogeneous suspension with a final concentration of 5 mg/ml.
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

溶剤液（一定の濃度）を調合する

生物活性

製品説明 Dipyridamole is a phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells.

プロトコル(参考用のみ)

参考

  • https://pubmed.ncbi.nlm.nih.gov/6628545/

Selleckの高級品が、幾つかの出版された研究調査結果（以下を含む）で使われた：

Adenosine signalling drives antidepressant actions of ketamine and ECT [ Nature, 2025, 10.1038/s41586-025-09755-9] PubMed: 41193806
Characterization of dipyridamole as a novel ferroptosis inhibitor and its therapeutic potential in acute respiratory distress syndrome management [ Theranostics, 2024, 14(18):6947-6968] PubMed: 39629132
Propafenone facilitates mitochondrial-associated ferroptosis and synergizes with immunotherapy in melanoma [ J Immunother Cancer, 2024, 12(11)e009805] PubMed: 39581704
Retinoblastoma vulnerability to combined de novo and salvage pyrimidine ribonucleotide synthesis pharmacologic blockage [ Heliyon, 2024, 10(1):e23831] PubMed: 38332874
Simultaneous inhibition of Sirtuin 3 and cholesterol homeostasis targets acute myeloid leukemia stem cells by perturbing fatty acid β-oxidation and inducing lipotoxicity [ Haematologica, 2023, 108(9):2343-2357] PubMed: 37021547
Suppression of cell pyroptosis by omeprazole through PDE4-mediated autophagy in gastric epithelial cells. [ BIOCELL, 2023, 47(12): 2709-2719] PubMed: none
Histone methyltransferase GLP epigenetically activatesGPCPD1to sustain cancer cell metastasis and invasion [ Genome Instability & Disease, 2023, 4, 21–37] PubMed: None
Histone methyltransferase GLP epigenetically activates GPCPD1 to sustain cancer cell metastasis and invasion [ Genome Instability & Disease , 2023, 4:21–37 ] PubMed: none
Wnt7b-induced Sox11 functions enhance self-renewal and osteogenic commitment of bone marrow mesenchymal stem cells [ Stem Cells, 2020, 38(8):1020-1033] PubMed: 32346881
Wnt7b-induced Sox11 functions enhance self-renewal and osteogenic commitment of bone marrow mesenchymal stem cells. [ Stem Cells, 2020, 28] PubMed: 32346881

長期の保管のために-20°Cの下で製品を保ってください。

人間や獣医の診断であるか治療的な使用のためにでない。

各々の製品のための特定の保管と取扱い情報は、製品データシートの上で示されます。大部分のSelleck製品は、推薦された状況の下で安定です。製品は、推薦された保管温度と異なる温度で、時々出荷されます。長期の保管のために必要とされてそれと異なる温度で、多くの製品は、短期もので安定です。品質を維持するが、夜通しの積荷のために最も経済的な貯蔵状況を用いてあなたの送料を保存する状況の下に、製品が出荷されることを、我々は確実とします。製品の受領と同時に、製品データシートの上で貯蔵推薦に従ってください。