L-Ascorbyl 6-palmitate

製品コードS2532 バッチS253201

印刷

化学情報

Chemical Structure Synonyms N/A Storage
(From the date of receipt)		 3 years -20°C powder
1 years -80°C in solvent
化学式

C22H38O7
分子量 414.53 CAS No. 137-66-6
Solubility (25°C)* 体外 DMSO 83 mg/mL (200.22 mM)
Ethanol 83 mg/mL (200.22 mM)
Water Insoluble
体内 （毎回新しく調製した物を用意してください）
Homogeneous suspension
CMC-NA
≥5mg/ml Taking the 1 mL working solution as an example, add 5 mg of this product to 1 ml of CMC-Na solution, mix evenly to obtain a homogeneous suspension with a final concentration of 5 mg/ml.
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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生物活性

製品説明 Ascorbyl palmitate is an ester formed from ascorbic acid and palmitic acid creating a fat-soluble form of vitamin C.
in vitro L-Ascorbyl 6-palmitate is a synthetic lipophilic ascorbic acid derivative. This compound is an effective preservative in foods and an effective dietary antitumor promoter in mice. Studies indicate that dietary this chemical is a source of tissue vitamin C in animals. Besides, dietary it possesses weak antiscorbutic activity in guinea pigs and enhances vitamin C nutriture in humans. [1]
in vivo In a study, daily mean weight loss during repletion in control animals receiving placebo is significantly greater than that for L-Ascorbyl 6-palmitate animals for days 3–10 of repletion. Daily mean weight loss for this compound animals is significantly greater than that for L-ascorbic acid (AA) animals on days 5 and 6 of repletion. By comparing areas of the weight-time curve during repletion, this compound appeares to be about 50% as effective as L-ascorbic acid (AA) in reversing scurvy. [2]

プロトコル(参考用のみ)

動物実験 動物モデル Male MF1 mice
投薬量 1412 mg/kg
投与方法 Orally

参考

  • http://www.sciencedirect.com/science/article/pii/S027153170580226X
  • https://pubmed.ncbi.nlm.nih.gov/3188040/

長期の保管のために-20°Cの下で製品を保ってください。

人間や獣医の診断であるか治療的な使用のためにでない。

各々の製品のための特定の保管と取扱い情報は、製品データシートの上で示されます。大部分のSelleck製品は、推薦された状況の下で安定です。製品は、推薦された保管温度と異なる温度で、時々出荷されます。長期の保管のために必要とされてそれと異なる温度で、多くの製品は、短期もので安定です。品質を維持するが、夜通しの積荷のために最も経済的な貯蔵状況を用いてあなたの送料を保存する状況の下に、製品が出荷されることを、我々は確実とします。製品の受領と同時に、製品データシートの上で貯蔵推薦に従ってください。