Baicalin

製品コードS2269 バッチS226901

印刷

化学情報

Chemical Structure Synonyms N/A Storage
(From the date of receipt)		 3 years -20°C powder
1 years -80°C in solvent
化学式

C21H18O11
分子量 446.36 CAS No. 21967-41-9
Solubility (25°C)* 体外 DMSO 89 mg/mL (199.39 mM)
Water Insoluble
Ethanol Insoluble
体内 （毎回新しく調製した物を用意してください）
Homogeneous suspension
CMC-NA
≥5mg/ml Taking the 1 mL working solution as an example, add 5 mg of this product to 1 ml of CMC-Na solution, mix evenly to obtain a homogeneous suspension with a final concentration of 5 mg/ml.
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

溶剤液（一定の濃度）を調合する

生物活性

製品説明 Baicalin is an inhibitor of prolyl oligopeptidase and also is an allosteric activator of carnitine palmityl transferase 1 (CPT1). Baicalin reduces the expression of NF-κB.

プロトコル(参考用のみ)

参考

  • https://pubmed.ncbi.nlm.nih.gov/18650094/
  • https://pubmed.ncbi.nlm.nih.gov/29891721/

Selleckの高級品が、幾つかの出版された研究調査結果（以下を含む）で使われた：

Baicalin reduces sunitinib-induced cardiotoxicity in renal carcinoma PDX model by inhibiting myocardial injury, apoptosis and fibrosis [ Front Pharmacol, 2025, 16:1563194] PubMed: 40264678
In Silico and In Vitro multiple analysis approach for screening naturally derived ligands for red seabream aryl hydrocarbon receptor [ Ecotoxicol Environ Saf, 2024, 275:116262] PubMed: 38569320
Baicalin exerts neuroprotective actions by regulating the Nrf2-NLRP3 axis in toxin-induced models of Parkinson's disease [ Chem Biol Interact, 2024, 387:110820] PubMed: 38016618
Baicalin Attenuates H2O2-Induced Oxidative Stress by Regulating the AMPK/Nrf2 Signaling Pathway in IPEC-J2 Cells [ Int J Mol Sci, 2023, 24(11)9435] PubMed: 37298392
Divergent and Overlapping Roles for Selected Phytochemicals in the Regulation of Pathological Cardiac Hypertrophy [ Molecules, 2021, 26(5)1210] PubMed: 33668293
Enteral nutrition ameliorates the symptoms of Crohn's disease in mice via activating special pro-resolving mediators through innate lymphoid cells [ Innate Immun, 2021, 27(7-8):533-542] PubMed: 34791916
An antiviral drug screening system for enterovirus 71 based on an improved plaque assay: A potential high-throughput method [ J Med Virol, 2019, 91(8):1440-1447] PubMed: 30900754
Baicalin improves IVM of pig oocytes and subsequent preimplantation embryo development by inhibiting apoptosis. [ Reprod Fertil Dev, 2019, 31(5):983-992] PubMed: 30819322
Chroman-like cyclic prenylflavonoids promote neuronal differentiation and neurite outgrowth and are neuroprotective. [Oberbauer E, et al. J Nutr Biochem, 2013, 24(11):1953-62] PubMed: 24070601

長期の保管のために-20°Cの下で製品を保ってください。

人間や獣医の診断であるか治療的な使用のためにでない。

各々の製品のための特定の保管と取扱い情報は、製品データシートの上で示されます。大部分のSelleck製品は、推薦された状況の下で安定です。製品は、推薦された保管温度と異なる温度で、時々出荷されます。長期の保管のために必要とされてそれと異なる温度で、多くの製品は、短期もので安定です。品質を維持するが、夜通しの積荷のために最も経済的な貯蔵状況を用いてあなたの送料を保存する状況の下に、製品が出荷されることを、我々は確実とします。製品の受領と同時に、製品データシートの上で貯蔵推薦に従ってください。