Troxerutin

製品コードS2369 バッチS236902

印刷

化学情報

Synonyms

N/A

Storage
(From the date of receipt)

3 years -20°C powder
1 years -80°C in solvent

化学式

C₃₃H₄₂O₁₉

分子量

742.68

CAS No.

7085-55-4

Solubility (25°C)*

体外

DMSO

100 mg/mL (134.64 mM)

Water (warmed with 50ºC water bath)

100 mg/mL (134.64 mM)

Ethanol

Insoluble

体内（毎回新しく調製した物を用意してください）

Homogeneous suspension	CMC-NA	≥5mg/ml	Taking the 1 mL working solution as an example, add 5 mg of this product to 1 ml of CMC-Na solution, mix evenly to obtain a homogeneous suspension with a final concentration of 5 mg/ml.
Clear solution	5%DMSO 1 40%PEG300 2 5%Tween80 3 50%ddH2O この製剤はselleckのラボで検証済みです。上記の溶解方法がご要望を満たさない場合、selleckの営業担当までお問い合わせ頂ければ、個別の試験を行います。	5mg/ml (6.73mM)	Taking the 1 mL working solution as an example, add 50 μL of 100 mg/ml clarified DMSO stock solution to 400 μL of PEG300, mix evenly to clarify it; add 50 μL of Tween80 to the above system, mix evenly to clarify; then continue to add 500 μL of ddH2O to adjust the volume to 1 mL. The mixed solution should be used immediately for optimal results.
Clear solution	5% DMSO 1 95% Corn oil この製剤はselleckのラボで検証済みです。上記の溶解方法がご要望を満たさない場合、selleckの営業担当までお問い合わせ頂ければ、個別の試験を行います。	0.71mg/ml (0.96mM)	Taking the 1 mL working solution as an example, add 50 μL of 14.2 mg/ml clear DMSO stock solution to 950 μL of corn oil and mix evenly. The mixed solution should be used immediately for optimal results.

* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

溶剤液（一定の濃度）を調合する

生物活性

製品説明	ソフォラジャポニカから単離された天然のバイオフラボノイドであるTroxerutinは、多くの利点と薬効があることが報告されています。
in vitro	Troxerutin (Trihydroxyethylrutin), a natural bioflavonoid isolated from Sophora japonica, has been reported to have many benefits and medicinal properties. This compound reduces homocysteine, alpha-amino adipic acid, cholesterol, triglycerides, and LDL apo B levels in plasma of patients of acute myocardial infarction. It decreases erythrocyte aggregation and shows positive action on stasis, capillary perfusion and trophic complications of chronic venous insufficiency. It also attenuates cognitive impairment and oxidative stress induced by D-galactose in mouse brain through decreasing advanced glycation end products, reactive oxygen species and protein carbonyl levels and enhancing phosphoinositide 3-kinase/Akt activation.

製品説明

ソフォラジャポニカから単離された天然のバイオフラボノイドであるTroxerutinは、多くの利点と薬効があることが報告されています。

in vitro

Troxerutin (Trihydroxyethylrutin), a natural bioflavonoid isolated from Sophora japonica, has been reported to have many benefits and medicinal properties. This compound reduces homocysteine, alpha-amino adipic acid, cholesterol, triglycerides, and LDL apo B levels in plasma of patients of acute myocardial infarction. It decreases erythrocyte aggregation and shows positive action on stasis, capillary perfusion and trophic complications of chronic venous insufficiency. It also attenuates cognitive impairment and oxidative stress induced by D-galactose in mouse brain through decreasing advanced glycation end products, reactive oxygen species and protein carbonyl levels and enhancing phosphoinositide 3-kinase/Akt activation.

プロトコル(参考用のみ)

参考

https://pubmed.ncbi.nlm.nih.gov/2930611/
https://pubmed.ncbi.nlm.nih.gov/7593149/
https://pubmed.ncbi.nlm.nih.gov/21252113/

Selleckの高級品が、幾つかの出版された研究調査結果（以下を含む）で使われた：

Propafenone facilitates mitochondrial-associated ferroptosis and synergizes with immunotherapy in melanoma [ J Immunother Cancer, 2024, 12(11)e009805]	PubMed: 39581704
Troxerutin suppresses the inflammatory response in advanced glycation end-product-administered chondrocytes and attenuates mouse osteoarthritis development. [ Food Funct, 2019, 10(8):5059-5069]	PubMed: 31359010

長期の保管のために-20°Cの下で製品を保ってください。

人間や獣医の診断であるか治療的な使用のためにでない。

各々の製品のための特定の保管と取扱い情報は、製品データシートの上で示されます。大部分のSelleck製品は、推薦された状況の下で安定です。製品は、推薦された保管温度と異なる温度で、時々出荷されます。長期の保管のために必要とされてそれと異なる温度で、多くの製品は、短期もので安定です。品質を維持するが、夜通しの積荷のために最も経済的な貯蔵状況を用いてあなたの送料を保存する状況の下に、製品が出荷されることを、我々は確実とします。製品の受領と同時に、製品データシートの上で貯蔵推薦に従ってください。