Adalimumab (anti-TNF-alpha)

製品コード：A2010         Batch: A201001

印刷

Adalimumab is the first fully human, recombinant IgG1 monoclonal antibody that specifically targets human TNF-alpha, MW: 144.19 KD.

製品説明

CAS No. 331731-18-1
Formulation 100 mM Pro, 20 mM Arg, pH 5.0
Isotype Human IgG1
Source CHO cells
Storage
(From the date of receipt)		 Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles
Shipping Shipped under low temperature conditions
Purity 99.12%
Protein concentration 5.0 mg/ml
Endotoxin Level ≤1 EU/mg

Selleckの高級品が、幾つかの出版された研究調査結果（以下を含む）で使われた：

ADA2-deficient cells exhibit increased levels of cell death and metabolic disturbances [ Cell Death Discov, 2026, 12(1)167] PubMed: 41866403
High Concentrations of β2-Microglobulin Do Not Inhibit In Vitro Generation of Functional Dendritic Cells [ J Immunol Res, 2026, 2026:2924555] PubMed: 41503517
Tumor necrosis factor from leukemic environment stimulates hematopoietic stem/progenitor cells toward megakaryocyte/myeloid lineage bias [ Exp Hematol, 2026, 155:105332] PubMed: 41352655
JAK-STAT-activated, fratricide-resistant CAR-T cells targeting membrane-bound TNF effectively treat AML and solid tumors [ J Immunother Cancer, 2025, 13(7)e011067] PubMed: 40659447
THBS1high macrophages promote aortic aneurysm formation by orchestrating an inflammatory and smooth muscle cell phenotypic transition program in vascular Behçet's disease [ BMC Med, 2025, 23(1):631] PubMed: 41225543
Glycolytic reprogramming shapes the histone acetylation profile of activated CD4+ T cells in juvenile idiopathic arthritis [ Cell Rep, 2025, 44(2):115287] PubMed: 40009514
A scalable human gut-immune co-culture model for evaluating inflammatory bowel disease anti-inflammatory therapies [ SLAS Discov, 2025, 35:100248] PubMed: 40645586
High-Throughput Human Gut Immune Co-Culture Model for Evaluating Inflammatory Bowel Disease Anti-Inflammatory Therapies [ bioRxiv, 2025, 2025.05.14.654072] PubMed: 40462955
Autoimmunity in Down's syndrome via cytokines, CD4 T cells and CD11c+ B cells [ Nature, 2023, 615(7951):305-314] PubMed: 36813963
HS 3D-SeboSkin Model Enables the Preclinical Exploration of Therapeutic Candidates for Hidradenitis Suppurativa/Acne Inversa [ Pharmaceutics, 2023, 15(2)619] PubMed: 36839941

人間や獣医の診断であるか治療的な使用のためにでない。