Adalimumab (anti-TNF-alpha)

製品コード：A2010         Batch: A201005

印刷

Adalimumab is the first fully human, recombinant IgG1 monoclonal antibody that specifically targets human TNF-alpha, MW: 144.19 KD.

製品説明

CAS No. 331731-18-1
Formulation 100 mM Pro, 20 mM Arg, pH 5.0
Isotype Human IgG1
Source CHO cells
Storage
(From the date of receipt)		 Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles
Shipping Shipped under low temperature conditions
Purity 99%
Protein concentration 10.6mg/ml
Endotoxin Level ＜1EU/mg

Selleckの高級品が、幾つかの出版された研究調査結果（以下を含む）で使われた：

JAK-STAT-activated, fratricide-resistant CAR-T cells targeting membrane-bound TNF effectively treat AML and solid tumors [ J Immunother Cancer, 2025, 13(7)e011067] PubMed: 40659447
Glycolytic reprogramming shapes the histone acetylation profile of activated CD4+ T cells in juvenile idiopathic arthritis [ Cell Rep, 2025, 44(2):115287] PubMed: 40009514
A scalable human gut-immune co-culture model for evaluating inflammatory bowel disease anti-inflammatory therapies [ SLAS Discov, 2025, 35:100248] PubMed: 40645586
High-Throughput Human Gut Immune Co-Culture Model for Evaluating Inflammatory Bowel Disease Anti-Inflammatory Therapies [ bioRxiv, 2025, 2025.05.14.654072] PubMed: 40462955
Autoimmunity in Down's syndrome via cytokines, CD4 T cells and CD11c+ B cells [ Nature, 2023, 615(7951):305-314] PubMed: 36813963
Autoimmunity in Down's syndrome via cytokines, CD4 T cells and CD11c+ B cells [ Nature, 2023, 615(7951):305-314] PubMed: 36813963
Autoimmunity in Down's syndrome via cytokines, CD4 T cells and CD11c+ B cells [ Nature, 2023, 615(7951):305-314] PubMed: 36813963
HS 3D-SeboSkin Model Enables the Preclinical Exploration of Therapeutic Candidates for Hidradenitis Suppurativa/Acne Inversa [ Pharmaceutics, 2023, 15(2)619] PubMed: 36839941
Identification of hub necroptosis-related lncRNAs for prognosis prediction of esophageal carcinoma [ Aging (Albany NY), 2023, 15(11):4794-4819] PubMed: 37263709
Characterization and optimization of variability in a human colonic epithelium culture model [ bioRxiv, 2023, 2023.09.22.559007] PubMed: 37790345

人間や獣医の診断であるか治療的な使用のためにでない。