Allylthiourea

製品コードS4017 バッチS401701

印刷

化学情報

Synonyms

N/A

Storage
(From the date of receipt)

3 years -20°C powder
1 years -80°C in solvent

化学式

C₄H₈N₂S

分子量

116.18

CAS No.

109-57-9

Solubility (25°C)*

体外

DMSO

23 mg/mL (197.96 mM)

Ethanol

23 mg/mL (197.96 mM)

Water

Insoluble

体内（毎回新しく調製した物を用意してください）

Homogeneous suspension

CMC-NA

≥5mg/ml

Taking the 1 mL working solution as an example, add 5 mg of this product to 1 ml of CMC-Na solution, mix evenly to obtain a homogeneous suspension with a final concentration of 5 mg/ml.

* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

溶剤液（一定の濃度）を調合する

生物活性

製品説明	Allylthiourea は、アンモニア酸化を選択的に阻害する代謝阻害剤です。
in vitro	Allylthiourea selectively inhibits ammonia oxidation at concentrations 8-80 μM. This compound (1 μM) inhibits ammonia oxidation by 80%. Complete inhibition is observed at an Allylthiourea concentration of 86 μM. The inhibition of this chemical on ammonia oxidation probably acts through chelating the copper of the ammonia monooxygenase active site. It is able to produce soluble methane monooxygenase (sMMO) in the presence of copper. Addition of 25 μM this compound decreases intracellular copper by 48% in Methylosinus trichosporium OB3b, allowing sMMO production at Cu/biomass ratios normally not permitting sMMO synthesis, which achieves a plateau of 320 μmol naphthol formed per gram dry biomass per hour.

製品説明

Allylthiourea は、アンモニア酸化を選択的に阻害する代謝阻害剤です。

in vitro

Allylthiourea selectively inhibits ammonia oxidation at concentrations 8-80 μM. This compound (1 μM) inhibits ammonia oxidation by 80%. Complete inhibition is observed at an Allylthiourea concentration of 86 μM. The inhibition of this chemical on ammonia oxidation probably acts through chelating the copper of the ammonia monooxygenase active site. It is able to produce soluble methane monooxygenase (sMMO) in the presence of copper. Addition of 25 μM this compound decreases intracellular copper by 48% in Methylosinus trichosporium OB3b, allowing sMMO production at Cu/biomass ratios normally not permitting sMMO synthesis, which achieves a plateau of 320 μmol naphthol formed per gram dry biomass per hour.

プロトコル(参考用のみ)

参考

https://pubmed.ncbi.nlm.nih.gov/9603846/
https://pubmed.ncbi.nlm.nih.gov/2496288/
https://pubmed.ncbi.nlm.nih.gov/19107472/

長期の保管のために-20°Cの下で製品を保ってください。

人間や獣医の診断であるか治療的な使用のためにでない。

各々の製品のための特定の保管と取扱い情報は、製品データシートの上で示されます。大部分のSelleck製品は、推薦された状況の下で安定です。製品は、推薦された保管温度と異なる温度で、時々出荷されます。長期の保管のために必要とされてそれと異なる温度で、多くの製品は、短期もので安定です。品質を維持するが、夜通しの積荷のために最も経済的な貯蔵状況を用いてあなたの送料を保存する状況の下に、製品が出荷されることを、我々は確実とします。製品の受領と同時に、製品データシートの上で貯蔵推薦に従ってください。