Anifrolumab (Anti-IFNAR1)

製品コード：A2460 Batch: A246003

Anifrolumab (Anti-IFNAR1) is a human monoclonal antibody. It is a type I interferon (IFN) receptor antagonist, that blocks the activity of type I interferon. Anifrolumab can be used in research of systemic lupus erythematosus (SLE). MW: 145.5 KD.

製品説明

CAS No.	1326232-46-5
Formulation	100 mM Pro-Ac, 20mM Arg, pH5.0
Isotype	Human IgG1
Source	CHO
Storage (From the date of receipt)	Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.
Shipping	Shipped under low temperature conditions
Purity	99%
Protein concentration	5.001mg/ml
Endotoxin Level	＜1EU/mg

Selleckの高級品が、幾つかの出版された研究調査結果（以下を含む）で使われた：

Galectin-9-driven immune evasion constrains radiotherapy-induced systemic antitumor immunity [ Journal for ImmunoTherapy of Cancer, 2026, 14(7):e013675]	PubMed: 42398969
cGAS/STING signalling in macrophages aggravates obliterative bronchiolitis via an IFN-α-dependent mechanism after orthotopic tracheal transplantation in mice [ Clin Transl Med, 2025, 15(5):e70323]	PubMed: 40292672
The macrocyclic peptide rhesus theta defensin 1 activates interferon and antiviral pathways in human monocytes [ Journal of Leukocyte Biology, 2025, qiaf150]	PubMed: 41139211
A TLR7/9-IFNα-LDHB axis drives vital NET release and compromises antibacterial defense in lupus [ bioRxiv [Preprint], 2025, 2025.10.07.680928]	PubMed: 41279671

人間や獣医の診断であるか治療的な使用のためにでない。