Anti-FGFR4 / CD334

製品コード:A2494         Batch: A249401

印刷

Anti-FGFR4 / CD334 (U3-1784) is a human monoclonal antibody targeting FGFR4 (human fibroblast growth factor receptor 4), with potential antineoplastic activity. It blocks activation of FGFR4, which inhibits FGFR4-mediated signaling and leads to an inhibition of cell proliferation in FGFR4-overexpressing tumor cells. MW: 145.5 KD.

製品説明

Formulation 100 mM Pro-Ac, 20mM Arg, pH5.0
Isotype Human IgG1
Source CHO
Storage
(From the date of receipt)
Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.
Shipping Shipped under low temperature conditions
Purity 99%
Protein concentration 4.85mg/ml
Endotoxin Level <1EU/mg

Selleckの高級品が、幾つかの出版された研究調査結果(以下を含む)で使われた:

Targeting FGFR4 Abrogates HNF1A-driven Metastasis in Pancreatic Ductal Adenocarcinoma [ bioRxiv, 2025, 2025.02.06.636643] PubMed: 39974881

人間や獣医の診断であるか治療的な使用のためにでない。