Anti-human/mouse TGF-β-InVivo [1D11.16.8]

製品コード：A2113         Batch: A211307

印刷

The 1D11.16.8 monoclonal antibody reacts with mouse, human, rat, monkey, hamster, canine and bovine TGF-β (transforming growth factor beta) isoforms 1, 2 and 3.The 1D11.16.8 monoclonal antibody is a neutralizing antibody.

製品説明

Formulation PBS buffer, pH 7.0
Clone 1D11.16.8
Immunogen Bovine TGFβ isoform 2
Isotype Mouse IgG1,κ
Application in vivo/vitro TGFβ neutralization,WB
Source CHO
Murine Pathogen Screening Panel all targets tested yielded Negative Results: Theiler’s Murine Encephalomyelitis Virus, Ectromelia (Mousepox) Virus, Hantavirus, Polyomavirus, Sendai Virus, Mycoplasma pulmonis, Pneumonia Virus of Mice, K Virus, Mouse Parvovirus, Mouse Hepatitis Virus, Mouse Norovirus, Mouse Minute Virus, Mouse Cytomegalovirus, Mouse Adenovirus, Lactate Dehydrogenase-Elevating Virus, Reovirus Panel, Lymphocytic Choriomeningitis Virus, Mouse Rotavirus.
Storage
(From the date of receipt)		 Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles
Shipping Shipped under low temperature conditions
Sterility 0.2 μM filtered
Purity 99%
Protein concentration 7.61 mg/mL
Endotoxin Level ＜1EU/mg

Selleckの高級品が、幾つかの出版された研究調査結果（以下を含む）で使われた：

Single-cell and spatial dissection of precancerous lesions underlying the initiation process of oral squamous cell carcinoma [ Cell Discovery, March 13, 2023, 9(1):28] PubMed: 36914617
HBx hijacks the miR‐19a‐3p/BAMBI/TGF‐β1 axis to impair the anti‐tumour activity of CD4 + T cells in diffuse large B‐cell lymphoma [ Clinical and Translational Medicine, January 1, 2026, 16(1):e70578] PubMed: 41492119
Downregulated Smad3 signaling impairs the maturation of MO-MDSC in colorectal cancer [ Cell Death & Disease, December 8, 2025, 16(1):880] PubMed: 41360769
Colorectal Cancer Cells Promote de novo Glycine Synthesis for Collagen Production in Cancer‐Associated Fibroblasts by Secreting TGF‐β1 [ MedComm – Oncology, August 24, 2025, 4(3):e70037]
Depletion of macrophages during early postnatal development leads to disrupted tooth root development and altered Gli1⁺ MSC trajectory [ Cell Death & Disease, April 26, 2026, 17(1):555] PubMed: 42036413
HBx hijacks the miR-19a-3p/BAMBI/TGF-β1 axis to impair the anti-tumour activity of CD4+ T cells in diffuse large B-cell lymphoma [ Clinical and Translational Medicine, 2026, e70578] PubMed: 41492119
Pre-Clinical Assessment of SAR442257, a CD38/CD3xCD28 Trispecific T Cell Engager in Treatment of Relapsed/Refractory Multiple Myeloma [ Cells, 2024, 13(10)879] PubMed: 38786100
Pre-Clinical Assessment of SAR442257, a CD38/CD3xCD28 Trispecific T Cell Engager in Treatment of Relapsed/Refractory Multiple Myeloma [ Cells, 2024, 879] PubMed: 38786100
Single-cell and spatial dissection of precancerous lesions underlying the initiation process of oral squamous cell carcinoma [ Cell Discov, 2023, 9(1):28] PubMed: 36914617
Single-cell and spatial dissection of precancerous lesions underlying the initiation process of oral squamous cell carcinoma [ Cell Discovery, 2023, 28] PubMed: 36914617

人間や獣医の診断であるか治療的な使用のためにでない。