Anti-mouse CD3ε-InVivo

製品コード：A2104 Batch: A210409

The 145-2C11 monoclonal antibody reacts with mouse CD3ε which is a 20 kDa transmembrane cell-surface protein that belongs to the immunoglobulin superfamily. The 145-2C11 antibody has been shown to induce T lymphocyte activation, proliferation, and apoptosis in vitro via binding and stimulating the TCR. When used in vivo the antibody is reported to produce T cell activation, anergy or death.

製品説明

Formulation	PBS buffer, pH 7.0
Clone	145-2C11
Immunogen	Mouse BM10-37 cytotoxic T cells
Isotype	Armenian Hamster IgG1
Application	in vitro T cell stimulation/activation, IF, FCM, WB
Source	CHO
Storage (From the date of receipt)	Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles
Shipping	Shipped under low temperature conditions
Sterility	0.2 μM filtered
Purity	99%
Protein concentration	6.68 mg/mL
Endotoxin Level	＜1EU/mg

Selleckの高級品が、幾つかの出版された研究調査結果（以下を含む）で使われた：

Disruption of FGL2 induces TFEB-dependent lysosomal degradation of PD-L1 and enhances the efficacy of anti-PD1 therapy in hepatocellular carcinoma [ Cell Communication and Signaling, 2026, Online ahead of print]	PubMed: 41629991.0
Short-term starvation inhibits CD36 N-glycosylation and downregulates USP7 UFMylation to alleviate RBPJ-maintained T cell exhaustion in liver cancer [ Theranostics, 2025, 15(12):5931-5952]	PubMed: 40365281
Short-term starvation inhibits CD36 N-glycosylation and downregulates USP7 UFMylation to alleviate RBPJ-maintained T cell exhaustion in liver cancer [ Theranostics, 2025, 5931-5952]	PubMed: 40365281.0
CD3ε of a pan T cell marker involved in mouse Aspergillus fumigatus keratitis [ International Journal of Ophthalmology, 2024, 616-624]	PubMed: nan
CD3ε of a pan T cell marker involved in mouse Aspergillus fumigatus keratitis [ Int J Ophthalmol, 2024, 17(4):616-624]	PubMed: 38638265

人間や獣医の診断であるか治療的な使用のためにでない。