Anti-mouse CD3ε-InVivo

製品コード：A2104         Batch: A210409

印刷

The 145-2C11 monoclonal antibody reacts with mouse CD3ε which is a 20 kDa transmembrane cell-surface protein that belongs to the immunoglobulin superfamily. The 145-2C11 antibody has been shown to induce T lymphocyte activation, proliferation, and apoptosis in vitro via binding and stimulating the TCR. When used in vivo the antibody is reported to produce T cell activation, anergy or death.

製品説明

Formulation PBS buffer, pH 7.0
Clone 145-2C11
Immunogen Mouse BM10-37 cytotoxic T cells
Isotype Armenian Hamster IgG1
Application in vitro T cell stimulation/activation, IF, FCM, WB
Source CHO
Murine Pathogen Screening Panel all targets tested yielded Negative Results: Theiler’s Murine Encephalomyelitis Virus, Ectromelia (Mousepox) Virus, Hantavirus, Polyomavirus, Sendai Virus, Mycoplasma pulmonis, Pneumonia Virus of Mice, K Virus, Mouse Parvovirus, Mouse Hepatitis Virus, Mouse Norovirus, Mouse Minute Virus, Mouse Cytomegalovirus, Mouse Adenovirus, Lactate Dehydrogenase-Elevating Virus, Reovirus Panel, Lymphocytic Choriomeningitis Virus, Mouse Rotavirus.
Storage
(From the date of receipt)		 Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles
Shipping Shipped under low temperature conditions
Sterility 0.2 μM filtered
Purity 99%
Protein concentration 6.68 mg/mL
Endotoxin Level ＜1EU/mg

Selleckの高級品が、幾つかの出版された研究調査結果（以下を含む）で使われた：

Spatiotemporal Analysis of Mesenchymal Stem Cells Fate Determination by Inflammatory Niche Following Soft Tissue Injury at a Single-Cell Level [ Advanced Science, September 23, 2024, 11(43):e2310282] PubMed: 39308190
Near-infrared II fluorescence imaging of PD-L1 and VEGF for assessing and early prediction of “T+A” therapeutic responsiveness in hepatocellular carcinoma [ Materials Today Bio, June 1, 2026, 38:103228] PubMed: 42211064
Adipocyte OX40L promotes adipose T cell activation and insulin resistance in obesity [ Experimental & Molecular Medicine, July 6, 2026, 1-15] PubMed: 42409961
Adipocyte OX40L promotes adipose T cell activation and insulin resistance in obesity [ Experimental and Molecular Medicine, July 2026, nan] PubMed: 42409961
Adipocyte OX40L promotes adipose T cell activation and insulin resistance in obesity [ Experimental and Molecular Medicine, July 2026, Online ahead of print] PubMed: 42409961
Histone lactylation increases CXCL1 expression for neutrophil infiltration and immune escape in pancreatic cancer [ Nature Communications, February 9, 2026, 17(1):2526] PubMed: 41663394
Short-term starvation inhibits CD36 N-glycosylation and downregulates USP7 UFMylation to alleviate RBPJ-maintained T cell exhaustion in liver cancer [ Theranostics, April 28, 2025, 15(12):5931-5952] PubMed: 40365281
Disruption of FGL2 induces TFEB-dependent lysosomal degradation of PD-L1 and enhances the efficacy of anti-PD1 therapy in hepatocellular carcinoma [ Cell Communication and Signaling, 2026-02-02, 155] PubMed: 41629991
Disruption of FGL2 induces TFEB-dependent lysosomal degradation of PD-L1 and enhances the efficacy of anti-PD1 therapy in hepatocellular carcinoma [ Cell Communication and Signaling, 2026, Online ahead of print] PubMed: 41629991
Short-term starvation inhibits CD36 N-glycosylation and downregulates USP7 UFMylation to alleviate RBPJ-maintained T cell exhaustion in liver cancer [ Theranostics, 2025, 5931-5952] PubMed: 40365281

人間や獣医の診断であるか治療的な使用のためにでない。