Anti-mouse CD4-InVivo

製品コード：A2101 Batch: A210124

Anti-mouse CD4 antibody(Clone:GK1.5) reacts with mouse CD4, which is a 55 kDa cell surface type I membrane glycoprotein. CD4 is a co-receptor of the T cell receptor (TCR) and assists the latter in communicating with antigen-presenting cells.

製品説明

Formulation	PBS buffer, pH 6.5
Clone	GK1.5
Immunogen	Mouse CTL clone V4
Isotype	Rat IgG2b,κ
Application	In vivo CD4+ T cell depletion,FCM,WB
Storage (From the date of receipt)	Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles
Shipping	Shipped under low temperature conditions
Sterility	0.2 μM filtered
Purity	99%
Protein concentration	7.69 mg/ml
Endotoxin Level	＜1EU/mg

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Selleckの高級品が、幾つかの出版された研究調査結果（以下を含む）で使われた：

Anti-BCL2 therapy eliminates giant congenital melanocytic nevus by senolytic and immune induction [ Signal Transduct Target Ther, 2025, 10(1):161]	PubMed: 40374605
Targeting site-specific N-glycosylated B7H3 induces potent antitumor immunity [ Nat Commun, 2025, 16(1):3546]	PubMed: 40229277
BET inhibitor in combination with BCG vaccine enhances antitumor efficacy and orchestrates T cell reprogramming for melanoma [ Cell Rep Med, 2025, 6(3):101995]	PubMed: 40107246
CD47 antibody-armed oncolytic adenovirus promotes chimeric antigen receptor macrophage phagocytosis and antitumor immunity [ Exp Hematol Oncol, 2025, 14(1):106]	PubMed: 40814015
FLT3L combined with GM-CSF induced dendritic cells drive broad tumor-specific CD8+ T cell responses and remodel the tumor microenvironment to enhance anti-tumor efficacy [ Front Immunol, 2025, 16:1649891]	PubMed: 40977690
DOCK2 protects against bacterial sepsis by constraining T helper 1 response [ Front Immunol, 2025, 16:1527934]	PubMed: 40510337
Dual impacts of serine/glycine-free diet in enhancing antitumor immunity and promoting evasion via PD-L1 lactylation [ Cell Metab, 2024, S1550-4131(24)00415-7]	PubMed: 39577415
Low-inflammatory lipid nanoparticle-based mRNA vaccine elicits protective immunity against H5N1 high-pathogenicity avian influenza virus with reduced adverse reactions [ Mol Ther, 2024, S1525-0016(24)00831-1]	PubMed: 39690742
Blockage of L2HGDH-mediated S-2HG catabolism orchestrates macrophage polarization to elicit antitumor immunity [ Cell Rep, 2024, 43(6):114300]	PubMed: 38829739
HVEM in acute lymphocytic leukemia facilitates tumour immune escape by inhibiting CD8+ T cell function [ Cell Oncol (Dordr), 2024, 10.1007/s13402-024-00959-1]	PubMed: 38809326

人間や獣医の診断であるか治療的な使用のためにでない。