Anti-mouse CD4-InVivo

製品コード：A2101 Batch: A210126

Anti-mouse CD4 antibody(Clone:GK1.5) reacts with mouse CD4, which is a 55 kDa cell surface type I membrane glycoprotein. CD4 is a co-receptor of the T cell receptor (TCR) and assists the latter in communicating with antigen-presenting cells.

製品説明

Formulation	PBS buffer, pH 6.5
Clone	GK1.5
Immunogen	Mouse CTL clone V4
Isotype	Rat IgG2b,κ
Application	In vivo CD4+ T cell depletion,FCM,WB
Source	CHO
Murine Pathogen Screening Panel	all targets tested yielded Negative Results: Theiler’s Murine Encephalomyelitis Virus, Ectromelia (Mousepox) Virus, Hantavirus, Polyomavirus, Sendai Virus, Mycoplasma pulmonis, Pneumonia Virus of Mice, K Virus, Mouse Parvovirus, Mouse Hepatitis Virus, Mouse Norovirus, Mouse Minute Virus, Mouse Cytomegalovirus, Mouse Adenovirus, Lactate Dehydrogenase-Elevating Virus, Reovirus Panel, Lymphocytic Choriomeningitis Virus, Mouse Rotavirus.
Storage (From the date of receipt)	Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles
Shipping	Shipped under low temperature conditions
Sterility	0.2 μM filtered
Purity	99%
Protein concentration	7.45 mg/ml
Endotoxin Level	＜1EU/mg

カスタマーフィードバック

Selleckの高級品が、幾つかの出版された研究調査結果（以下を含む）で使われた：

FLT3L combined with GM-CSF induced dendritic cells drive broad tumor-specific CD8+ T cell responses and remodel the tumor microenvironment to enhance anti-tumor efficacy [ Frontiers in Immunology, September 4, 2025, 16:1649891]	PubMed: 40977690
Spatiotemporal Analysis of Mesenchymal Stem Cells Fate Determination by Inflammatory Niche Following Soft Tissue Injury at a Single‐Cell Level [ Advanced Science, September 23, 2024, 11(43):2310282]	PubMed: 39308190
LZTR1 regulates epithelial MHC-I expression via NF-κB1 to modulate CD8+ T cells activation [ Cell Discovery, October 29, 2025, 11(1):84]	PubMed: 41162356
TREM2-Mediated Cholesterol Efflux in Macrophages Inhibits Anti-Tumor Immunity via Limitation of CD4+ T and NK Cells [ Advanced Science, October 20, 2025, 13(5):e06995]	PubMed: 41114464
Oncolytic virus M1 functions as a bifunctional checkpoint inhibitor to enhance the antitumor activity of DC vaccine [ Cell Reports Medicine, October 1, 2023, 4(10):101229]	PubMed: 37820722
Silencing PCSK9 reshapes the spatiotemporal activation of STING for safe and effective cancer immunotherapy [ Nature Communications, November 25, 2025, 16(1):11622]	PubMed: 41290746
Low-dose radiotherapy combined with dual PD-L1 and VEGFA blockade elicits antitumor response in hepatocellular carcinoma mediated by activated intratumoral CD8+ exhausted-like T cells [ Nature Communications, November 24, 2023, 14(1):7709]	PubMed: 38001101
DOCK2 protects against bacterial sepsis by constraining T helper 1 response [ Frontiers in Immunology, May 29, 2025, 16:1527934]	PubMed: 40510337
Anti-BCL2 therapy eliminates giant congenital melanocytic nevus by senolytic and immune induction [ Signal Transduction and Targeted Therapy, May 16, 2025, 10(1):161]	PubMed: 40374605
HFB301001, an OX40-based immunotherapy, drives Treg clearance and CTL activation through optimized OX40 receptor clustering [ Journal for ImmunoTherapy of Cancer, March 30, 2026, e014185]	PubMed: 41912269

人間や獣医の診断であるか治療的な使用のためにでない。