Anti-mouse CD8α-InVivo

製品コード：A2102 Batch: A210234

Anti-mouse CD8α (Clone:2.43)reacts with mouse CD8α. CD8 is a transmembrane glycoprotein that acts as a co-receptor for the T cell receptor (TCR). It binds to class I MHC molecules displayed by antigen presenting cells (APC).

製品説明

Formulation	PBS buffer, pH 7.0
Clone	2.43
Immunogen	Mouse CTL clone L3
Isotype	Rat IgG2b, κ
Application	In vivo CD8+ T cell depletion,WB
Source	CHO
Murine Pathogen Screening Panel	all targets tested yielded Negative Results: Theiler’s Murine Encephalomyelitis Virus, Ectromelia (Mousepox) Virus, Hantavirus, Polyomavirus, Sendai Virus, Mycoplasma pulmonis, Pneumonia Virus of Mice, K Virus, Mouse Parvovirus, Mouse Hepatitis Virus, Mouse Norovirus, Mouse Minute Virus, Mouse Cytomegalovirus, Mouse Adenovirus, Lactate Dehydrogenase-Elevating Virus, Reovirus Panel, Lymphocytic Choriomeningitis Virus, Mouse Rotavirus.
Storage (From the date of receipt)	Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles
Shipping	Shipped under low temperature conditions
Sterility	0.2 μM filtered
Purity	99%
Protein concentration	7.86 mg/ml
Endotoxin Level	＜1EU/mg

カスタマーフィードバック

Selleckの高級品が、幾つかの出版された研究調査結果（以下を含む）で使われた：

Nuclear glycine decarboxylase suppresses STAT1-dependent MHC-I and promotes cancer immune evasion [ The EMBO Journal, September 8, 2025, 44(20):5712-5733]	PubMed: 40926122
Angiotensin receptor blocker attacks armored and cold tumors and boosts immune checkpoint blockade [ Journal for ImmunoTherapy of Cancer, September 6, 2024, e009327]	PubMed: 39244215
FLT3L combined with GM-CSF induced dendritic cells drive broad tumor-specific CD8+ T cell responses and remodel the tumor microenvironment to enhance anti-tumor efficacy [ Frontiers in Immunology, September 4, 2025, 16:1649891]	PubMed: 40977690
Spatiotemporal Analysis of Mesenchymal Stem Cells Fate Determination by Inflammatory Niche Following Soft Tissue Injury at a Single‐Cell Level [ Advanced Science, September 23, 2024, 11(43):2310282]	PubMed: 39308190
Radiation-induced upregulation of itaconate in macrophages promotes the radioresistance of non-small cell lung cancer by stabilizing NRF2 protein and suppressing immune response [ Redox Biology, September 1, 2025, 85:103711]	PubMed: 40482348
Urokinase-type plasminogen activator deficiency enhances CD8+ T cell infiltration and anti-PD-1 therapy efficacy in prostate cancer [ Frontiers in Immunology, September 1, 2025, 16:1625226]	PubMed: 40959092
Angiotensin receptor blocker attacks armored and cold tumors and boosts immune checkpoint blockade [ Journal for Immunotherapy of Cancer, September 1, 2024, 12(9):e009327]	PubMed: 39244215
Voluntary exercise sensitizes cancer immunotherapy via the collagen inhibition-orchestrated inflammatory tumor immune microenvironment [ Cell Reports, September 1, 2024, 43(9):114697]	PubMed: 39217611
Beta-1,4-galactosyltransferase-3 deficiency suppresses the growth of immunogenic tumors in mice [ Frontiers in Immunology, October 9, 2023, 14:1272537]	PubMed: 37901252
LZTR1 regulates epithelial MHC-I expression via NF-κB1 to modulate CD8+ T cells activation [ Cell Discovery, October 29, 2025, 11(1):84]	PubMed: 41162356

人間や獣医の診断であるか治療的な使用のためにでない。