Anti-mouse CTLA-4 (CD152)-InVivo

製品コード：A2103         Batch: A210312

印刷

Anti-mouse CTLA-4 (CD152) antibody (Clone:9H10) reacts with mouse CTLA-4 (cytotoxic T lymphocyte antigen-4) also known as CD152. Anti-mouse CTLA-4 (CD152) antibody has been shown to promote T cell co-stimulation by blocking CTLA-4 binding to the B7 co-receptors, allowing for CD28 binding.

製品説明

Formulation PBS buffer, pH 7.0
Clone 9H10
Immunogen Mouse CTLA-4-human IgG1 fusion protein
Isotype Syrian hamster IgG
Application in vivo/vitro CTLA-4 neutralization, FCM,WB
Source CHO
Murine Pathogen Screening Panel all targets tested yielded Negative Results: Theiler’s Murine Encephalomyelitis Virus, Ectromelia (Mousepox) Virus, Hantavirus, Polyomavirus, Sendai Virus, Mycoplasma pulmonis, Pneumonia Virus of Mice, K Virus, Mouse Parvovirus, Mouse Hepatitis Virus, Mouse Norovirus, Mouse Minute Virus, Mouse Cytomegalovirus, Mouse Adenovirus, Lactate Dehydrogenase-Elevating Virus, Reovirus Panel, Lymphocytic Choriomeningitis Virus, Mouse Rotavirus.
Storage
(From the date of receipt)		 Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles
Shipping Shipped under low temperature conditions
Sterility 0.2 μM filtered
Purity 99%
Protein concentration 12.55 mg/mL
Endotoxin Level ＜1EU/mg

Selleckの高級品が、幾つかの出版された研究調査結果（以下を含む）で使われた：

N-terminal acetylation of transcription factor LIP induces immune therapy resistance via suppression of PD-L1 expression in non-small cell lung cancer [ Journal for Immunotherapy of Cancer, November 1, 2024, 12(11):e009905] PubMed: 39615895
HBx hijacks the miR‐19a‐3p/BAMBI/TGF‐β1 axis to impair the anti‐tumour activity of CD4+ T cells in diffuse large B‐cell lymphoma [ Clinical and Translational Medicine, January 2026, e70578] PubMed: 41492119
HBx hijacks the miR‐19a‐3p/BAMBI/TGF‐β1 axis to impair the anti‐tumour activity of CD4 + T cells in diffuse large B‐cell lymphoma [ Clinical and Translational Medicine, January 1, 2026, 16(1):e70578] PubMed: 41492119
HE4 drives PD-L1 expression in myeloid cells via IFN-γR-JAK-STAT3 signaling to promote tumor immune evasion [ Cell Reports Medicine, April 1, 2026, 7(4):102691] PubMed: 41861828
N-terminal acetylation of transcription factor LIP induces immune therapy resistance via suppression of PD-L1 expression in non-small cell lung cancer [ J Immunother Cancer, 2024, 12(11)e009905] PubMed: 39615895

人間や獣医の診断であるか治療的な使用のためにでない。