Anti-mouse IFNAR-1-InVivo

製品コード：A2121 Batch: A212107

Anti-mouse IFNAR-1-InVivo monoclonal antibody (Clone: MAR1-5A3) reacts with mouse IFNAR-1 (IFN alpha/beta receptor subunit 1). Anti-mouse IFNAR-1-InVivo has been shown to inhibit Type I IFN receptor signaling in vitro and in vivo.

製品説明

Formulation	PBS Buffer, PH 7.4
Clone	MAR1-5A3
Immunogen	Extracellular domain of mouse IFNAR-1
Isotype	Mouse IgG1, κ
Application	in vivo IFNAR-1 blockade, in vitro IFNAR-1 blockade, WB
Source	CHO
Murine Pathogen Screening Panel	all targets tested yielded Negative Results: Theiler’s Murine Encephalomyelitis Virus, Ectromelia (Mousepox) Virus, Hantavirus, Polyomavirus, Sendai Virus, Mycoplasma pulmonis, Pneumonia Virus of Mice, K Virus, Mouse Parvovirus, Mouse Hepatitis Virus, Mouse Norovirus, Mouse Minute Virus, Mouse Cytomegalovirus, Mouse Adenovirus, Lactate Dehydrogenase-Elevating Virus, Reovirus Panel, Lymphocytic Choriomeningitis Virus, Mouse Rotavirus.
Storage (From the date of receipt)	Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles.
Shipping	Shipped under low temperature conditions
Sterility	0.2 μM filtered
Purity	99%
Protein concentration	6.03 mg/ml
Endotoxin Level	<1EU/mg

カスタマーフィードバック

Selleckの高級品が、幾つかの出版された研究調査結果（以下を含む）で使われた：

SBRT embedded in low-dose RT plus αPD-1 (immuno-EclipseRT, iERT) elicits CD8+ T cell immunity against bulky tumors via an IFN-I/NK/DC axis [ Nature Communications, July 8, 2026, 17(1):7568]	PubMed: 42420294
Targeting IFN-I driven tertiary lymphoid structures halts B cell-mediated bone loss in periodontitis [ International Journal of Oral Science, July 27, 2026, 18(1):53]	PubMed: 42503518
Type I IFN Dynamics Define an Early Checkpoint for Survival and Orchestrate Systemic Neutrophil Heterogeneity in Lethal Viral Infection [ nan, January 24, 2026, nan]
Type I interferon/STAT1 signaling regulates UBE2M-mediated antiviral innate immunity in a negative feedback manner [ Cell Reports, January 1, 2023, 42(1):112002]	PubMed: 36662617
Intrinsic STING of CD8 + T cells regulates self-metabolic reprogramming and memory to exert anti-tumor effects [ Cell Communication and Signaling, February 19, 2025, 23(1):99]	PubMed: 39972350
Targeting immune cells in the aged brain reveals that engineered cytokine IL-10 enhances neurogenesis and improves cognition [ Immunity, February 1, 2026, 59(2):458-476.e13]	PubMed: 41619730
sVEGFR1 up-regulation via EGR1 impairs vascular repair in SFTSV-induced hemorrhage [ EMBO Reports, August 11, 2025, 26(18):4477-4502]	PubMed: 40789964
Modulation of innate immune response to viruses including SARS-CoV-2 by progesterone [ Signal Transduction and Targeted Therapy, April 25, 2022, 7(1):137]	PubMed: 35468896
Targeting immune cells in the aged brain with engineered proteins reveals that engineered cytokine IL-10 enhances neurogenesis and improves cognition [ Immunity, 2026 Jan 30, 59(2):458–476.e13]	PubMed: 41619730
Intrinsic STING of CD8 + T cells regulates self-metabolic reprogramming and memory to exert anti-tumor effects [ Cell Commun Signal, 2025, 23(1):99]	PubMed: 39972350

人間や獣医の診断であるか治療的な使用のためにでない。