Anti-mouse IL-17A-InVivo

製品コード：A2120 Batch: A212007

Anti-mouse IL-17A-InVivo monoclonal antibody (Clone:17F3) reacts with mouse IL-17A which is a 15-20 kDa cytokine expressed by Th17 cells, γδ T cells, iNKT cells, NK cells, LTi cells, neutrophils, and intestinal Paneth cells. Anti-mouse IL-17A-InVivo has been shown to neutralize IL-17A in vivo.

製品説明

Formulation	PBS Buffer, PH 7.4
Clone	17F3
Immunogen	Mouse IL-17A cross-linked to OVA
Isotype	Mouse IgG1, κ
Application	in vivo IL-17A neutralization
Source	CHO
Murine Pathogen Screening Panel	all targets tested yielded Negative Results: Theiler’s Murine Encephalomyelitis Virus, Ectromelia (Mousepox) Virus, Hantavirus, Polyomavirus, Sendai Virus, Mycoplasma pulmonis, Pneumonia Virus of Mice, K Virus, Mouse Parvovirus, Mouse Hepatitis Virus, Mouse Norovirus, Mouse Minute Virus, Mouse Cytomegalovirus, Mouse Adenovirus, Lactate Dehydrogenase-Elevating Virus, Reovirus Panel, Lymphocytic Choriomeningitis Virus, Mouse Rotavirus.
Storage (From the date of receipt)	Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles.
Shipping	Shipped under low temperature conditions
Sterility	0.2 μM filtered
Purity	99%
Protein concentration	6.18 mg/ml
Endotoxin Level	＜1EU/mg

カスタマーフィードバック

Selleckの高級品が、幾つかの出版された研究調査結果（以下を含む）で使われた：

Keratinocyte-specific H4K12 lactylation drives a non-canonical IL-17-dependent signaling in psoriasis progression in mice [ Nature Communications, September 30, 2025, 16(1):8639]	PubMed: 41027887
Cardiac arrest triggers IL-17-mediated neuroinflammation and astrocyte polarization: insights into pathogenesis and intervention [ Journal of Neuroinflammation, November 14, 2025, 22(1):268]	PubMed: 41239323
Analysis and experimental validation of IL-17 pathway and key genes as central roles associated with inflammation in hepatic ischemia-reperfusion injury [ Scientific Reports, March 18, 2024, 14(1):6423]	PubMed: 38494504
Scleroglucan protects the intestine from irradiation-induced injury by targeting the IL-17 signaling pathway [ International Immunopharmacology, March 1, 2024, 129:111614]	PubMed: 38350358
IL-17 Signaling Pathway: A Potential Signaling Pathway Mediating Neuroinflammation Induced by PM 2.5 [ Environment & Health, June 3, 2026, nan]
The IL-17A/Neutrophil axis plays a critical role in lethal infection induced by an emerging ultra-virulent Streptococcus suis serotype 5 strain [ Virulence, June 21, 2026, 17(1)]	PubMed: 42308351
Fungal pathogen-responsive Th17 cells in gut-mouth axis enhance protection against oropharyngeal candidiasis [ iScience, June 1, 2025, 28(6):112675]	PubMed: 40510134
Engineered probiotics platform for oral delivery of antibody as a high-compliance alternative for immune-mediated inflammatory diseases [ Cell Reports Medicine, January 1, 2026, 7(1):102523]	PubMed: 41421354
Immunotherapy-induced sialadenitis: sjögren’s syndrome or a new sialadenitis [ Frontiers in Immunology, February 27, 2026, 17:1755419]	PubMed: 41836391
Th17 cells/IL-17A shape Pasteurella multocida serotype A infection in murine and rabbit models [ Veterinary Research, December 16, 2025, 56(1):229]	PubMed: 41402924

人間や獣医の診断であるか治療的な使用のためにでない。