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受注:045-509-1970 |
技術サポート:tech@selleck.co.jp 平日9:00〜18:00 1営業日以内にご連絡を差し上げます |
製品コード:A2118 Batch: A211809
Anti-mouse IL-6-InVivo monoclonal antibody (Clone:MP5-20F3) can reacts with mouse IL-6 (interleukin-6) which is a 21-28 kDa cytokine that is expressed by many cell types, including T lymphocytes, B lymphocytes, monocytes, fibroblasts, and endothelial cells. Anti-mouse IL-6-InVivo has been shown to neutralize the bioactivity of natural or recombinant IL-6.
| Formulation | PBS Buffer, PH 7.4 |
|---|---|
| Clone | MP5-20F3 |
| Immunogen | Recombinant mouse IL-6 |
| Isotype | Rat IgG1, κ |
| Application | in vivo IL-6 neutralization |
| Source | CHO |
| Storage (From the date of receipt) |
Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles. |
| Shipping | Shipped under low temperature conditions |
| Sterility | 0.2 μM filtered |
| Purity | 99% |
| Protein concentration | 6.33 mg/mL |
| Endotoxin Level | <1 EU/mg |

| Macrophage STING signaling promotes fibrosis in benign airway stenosis via an IL6-STAT3 pathway [ Nat Commun, 2025, 16(1):289] | PubMed: 39753529 |
| Iron overload in CD11c+ myeloid cells exacerbates acetaminophen hepatotoxicity [ Commun Biol, 2025, 8(1):1488] | PubMed: 41120657 |
| SR-717, a Non-Nucleotide STING Agonist, Displayed Anti-Radiation Activity in a IL-6 Dependent Manner [ FASEB J, 2025, 39(11):e70644] | PubMed: 40448435 |
| Targeting RPE Senescence Via Suppressing IL-6/IL-6R Signaling for Treating Retinal Degenerative Diseases [ Invest Ophthalmol Vis Sci, 2025, 66(12):44] | PubMed: 40970669 |
| Circulating Interleukin-6 Mediates PM2.5-Induced Ovarian Injury by Suppressing the PPARγ Pathway [ Research (Wash D C), 2024, 7:0538] | PubMed: 39639885 |
| The increase of long noncoding RNA Fendrr in hepatocytes contributes to liver fibrosis by promoting IL-6 production [ J Biol Chem, 2024, S0021-9258(24)01877-5] | PubMed: 38762176 |
| The increase of long noncoding RNA Fendrr in hepatocytes contributes to liver fibrosis by promoting IL-6 production [ J Biol Chem, 2024, 300(6):107376] | PubMed: 38762176 |
人間や獣医の診断であるか治療的な使用のためにでない。