Anti-mouse IL-6-InVivo [MP5-20F3]

製品コード：A2118 Batch: A211811

Anti-mouse IL-6-InVivo [MP5-20F3] can reacts with mouse IL-6 (interleukin-6) which is a 21-28 kDa cytokine that is expressed by many cell types, including T lymphocytes, B lymphocytes, monocytes, fibroblasts, and endothelial cells. Anti-mouse IL-6-InVivo has been shown to neutralize the bioactivity of natural or recombinant IL-6.

製品説明

Formulation	PBS Buffer, PH 7.4
Clone	MP5-20F3
Immunogen	Recombinant mouse IL-6
Isotype	Rat IgG1, κ
Application	in vivo IL-6 neutralization
Source	CHO
Murine Pathogen Screening Panel	all targets tested yielded Negative Results: Theiler’s Murine Encephalomyelitis Virus, Ectromelia (Mousepox) Virus, Hantavirus, Polyomavirus, Sendai Virus, Mycoplasma pulmonis, Pneumonia Virus of Mice, K Virus, Mouse Parvovirus, Mouse Hepatitis Virus, Mouse Norovirus, Mouse Minute Virus, Mouse Cytomegalovirus, Mouse Adenovirus, Lactate Dehydrogenase-Elevating Virus, Reovirus Panel, Lymphocytic Choriomeningitis Virus, Mouse Rotavirus.
Storage (From the date of receipt)	Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles.
Shipping	Shipped under low temperature conditions
Sterility	0.2 μM filtered
Purity	99%
Protein concentration	4.70 mg/ml
Endotoxin Level	＜1EU/mg

カスタマーフィードバック

Selleckの高級品が、幾つかの出版された研究調査結果（以下を含む）で使われた：

Targeting RPE Senescence Via Suppressing IL-6/IL-6R Signaling for Treating Retinal Degenerative Diseases [ Investigative Ophthalmology & Visual Science, September 2025, Vol.66, 44]	PubMed: 40970669
Targeting RPE Senescence Via Suppressing IL-6/IL-6R Signaling for Treating Retinal Degenerative Diseases [ Investigative Ophthalmology & Visual Science, September 19, 2025, 66(12):44]	PubMed: 40970669
Iron overload in CD11c+ myeloid cells exacerbates acetaminophen hepatotoxicity [ Communications Biology, October 21, 2025, 8(1):1488]	PubMed: 41120657
Calcitonin receptor downregulation and exercise-conditioned blood enable systemic muscle stem cell proliferation [ Nature Communications, November 26, 2025, 16(1):10576]	PubMed: 41298450
Oncolytic virus-induced IL-1β+ monocyte-IL-6+ CAF axis suppresses dendritic cell-mediated antitumor immunity in pancreatic cancer [ Journal for Immunotherapy of Cancer, November 1, 2025, 13(11):e013175]	PubMed: 41253490
SR-717, a Non-Nucleotide STING Agonist, Displayed Anti-Radiation Activity in a IL-6 Dependent Manner [ The FASEB Journal, May 31, 2025, 39(11):e70644]	PubMed: 40448435
Targeting CD177: A Novel Therapeutic Strategy for NLRP3-Associated Autoinflammatory Diseases [ International Journal of Molecular Sciences, March 20, 2026, 27(6):2841]	PubMed: 41898699
Disruption of the Na+/K+-ATPase-purinergic P2X7 receptor complex in microglia promotes stress-induced anxiety [ Immunity, March 1, 2024, 57(3):495-512.e11]	PubMed: 38395698
The increase of long noncoding RNA Fendrr in hepatocytes contributes to liver fibrosis by promoting IL-6 production [ The Journal of Biological Chemistry, June 1, 2024, 300(6):107376]	PubMed: 38762176
Macrophage STING signaling promotes fibrosis in benign airway stenosis via an IL6-STAT3 pathway [ Nature Communications, January 3, 2025, 16(1):289]	PubMed: 39753529

人間や獣医の診断であるか治療的な使用のためにでない。