Anti-mouse LFA-1α (CD11a)-InVivo

製品コード：A2130         Batch: A213003

印刷

Anti-mouse LFA-1α (CD11a)-InVivo(clone M17/4) is a monoclonal antibody reacts with mouse LFA-1α (lymphocyte function-associated antigen 1 alpha) also known as integrin alpha L chain and CD11a. It plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAM-1 (CD54), ICAM-2 (CD102), and ICAM-3 (CD50), and also functions in lymphocyte costimulatory signaling.

製品説明

Formulation PBS, pH 7.0 Contains no stabilizers or preservatives
Clone M17/4
Isotype Rat IgG2a, κ
Application Anti-mouse LFA-1α (CD11a)-InVivo
Source CHO
Murine Pathogen Screening Panel all targets tested yielded Negative Results: Theiler’s Murine Encephalomyelitis Virus, Ectromelia (Mousepox) Virus, Hantavirus, Polyomavirus, Sendai Virus, Mycoplasma pulmonis, Pneumonia Virus of Mice, K Virus, Mouse Parvovirus, Mouse Hepatitis Virus, Mouse Norovirus, Mouse Minute Virus, Mouse Cytomegalovirus, Mouse Adenovirus, Lactate Dehydrogenase-Elevating Virus, Reovirus Panel, Lymphocytic Choriomeningitis Virus, Mouse Rotavirus.
Storage
(From the date of receipt)		 Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles
Shipping Shipped under low temperature conditions
Sterility 0.2 μM filtered
Purity 99%
Protein concentration 6.50 mg/ml
Endotoxin Level <1EU/mg

Selleckの高級品が、幾つかの出版された研究調査結果（以下を含む）で使われた：

Low-dose radiotherapy synergizes with PD-1 blockade to achieve durable survival in advanced NSCLC through antitumor neutrophil programming [ Signal Transduction and Targeted Therapy, May 7, 2026, 11(1):170] PubMed: 42091852
Neutralizing LFA-1 alleviates acute lung injury by diminishing pulmonary retention of CAR-T cells [ Pharmacological Research, August 1, 2026, 230:108292] PubMed: 42285385

人間や獣医の診断であるか治療的な使用のためにでない。