Anti-mouse PD-1 (CD279)-InVivo [RMP1-14]

製品コード：A2122        

印刷

Anti-mouse PD-1 (CD279)-InVivo [RMP1-14] reacts with mouse PD-1 (programmed death-1) also known as CD279. PD-1 is a 50-55 kDa cell surface receptor encoded by the Pdcd1 gene that belongs to the CD28 family of the Ig superfamily.

製品説明

Molecular Weight 150 kDa
Formulation PBS Buffer, PH 7.4
Clone RMP1-14
Isotype Rat IgG2a, κ
Application in vivo blocking of PD-1/PD-L signaling
Source CHO
Murine Pathogen Screening Panel all targets tested yielded Negative Results: Theiler’s Murine Encephalomyelitis Virus, Ectromelia (Mousepox) Virus, Hantavirus, Polyomavirus, Sendai Virus, Mycoplasma pulmonis, Pneumonia Virus of Mice, K Virus, Mouse Parvovirus, Mouse Hepatitis Virus, Mouse Norovirus, Mouse Minute Virus, Mouse Cytomegalovirus, Mouse Adenovirus, Lactate Dehydrogenase-Elevating Virus, Reovirus Panel, Lymphocytic Choriomeningitis Virus, Mouse Rotavirus.
Storage
(From the date of receipt)		 Store the undiluted solution at 4°C and avoid freeze-thaw cycle
Shipping Shipped under low temperature conditions
Purification Protein G
Sterility 0.2 μM filtered

カスタマーフィードバック

A2122-Anti-mouse PD-1 (CD279)-InVivo.gif

Selleckの高級品が、幾つかの出版された研究調査結果（以下を含む）で使われた：

Co-inhibition of PGF and VEGFA enhances the effectiveness of immunotherapy in bladder cancer [ International Journal of Medical Sciences, October 28, 2024, 21(15):2870-2882] PubMed: 39628692
EIF2B4 promotes hepatocellular carcinoma progression and immune evasion by driving STAT3 translation via a GEF-dependent mechanism [ Cellular Oncology, October 27, 2025, 48(6):1919-1933] PubMed: 41144132
Characteristics of tertiary lymphoid structures in prostate cancer and the impact of neoadjuvant therapy on their formation and maturation [ Frontiers in Immunology, November 4, 2025, 16:1663396] PubMed: 41262256
Yin Yang 1 Promotes Antiprogrammed Cell Death-1 Resistance in Hepatocellular Carcinoma through Polypeptide N-Acetylgalactosaminyltransferase 16-Mediated Glycosylation of Programmed Death Ligand-1 [ MedComm, November 26, 2025, 6(12):e70504] PubMed: 41322030
ZDHHC3-mediated SCAP S-acylation promotes cholesterol biosynthesis and tumor immune escape in hepatocellular carcinoma [ Cell Reports, November 1, 2024, 43(11):114962] PubMed: 39522165
Low-dose radiotherapy synergizes with PD-1 blockade to achieve durable survival in advanced NSCLC through antitumor neutrophil programming [ Signal Transduction and Targeted Therapy, May 7, 2026, 11(1):170] PubMed: 42091852
Betrixaban activates cGAS-STING to promote antitumor immunity without pathological inflammation [ EMBO Molecular Medicine, May 14, 2026, 18(6):2213-2235] PubMed: 42135568
CDK4/6 inhibitor abemaciclib combined with low-dose radiotherapy enhances the anti-tumor immune response to PD-1 blockade by inflaming the tumor microenvironment in Rb-deficient small cell lung cancer [ Translational Lung Cancer Research, May 1, 2024, 13(5):1032-1046] PubMed: 38854937
CCL5 hi CD4 + T Cells Regulate Macrophage Polarization and Promote Immunotherapy Response in Bladder Cancer [ Cancer Immunology Research, May 04, 2026, nan]
Oncolytic virus M1 reinvigorates CD8+ T-cell immunity against glioblastoma through B-cell-dependent antigen cross-presentation in the spleen [ Cellular and Molecular Immunology, March 4, 2026, 23(4):349-366] PubMed: 41781696

人間や獣医の診断であるか治療的な使用のためにでない。