Anti-mouse PD-1 (CD279)-InVivo

製品コード：A2122         Batch: A212274

印刷

Anti-mouse PD-1 (CD279)-InVivo (Clone:RMP1-14)reacts with mouse PD-1 (programmed death-1) also known as CD279. PD-1 is a 50-55 kDa cell surface receptor encoded by the Pdcd1 gene that belongs to the CD28 family of the Ig superfamily.

製品説明

Formulation PBS Buffer, PH 7.4
Clone RMP1-14
Isotype Rat IgG2a, κ
Application in vivo blocking of PD-1/PD-L signaling
Source CHO
Murine Pathogen Screening Panel all targets tested yielded Negative Results: Theiler’s Murine Encephalomyelitis Virus, Ectromelia (Mousepox) Virus, Hantavirus, Polyomavirus, Sendai Virus, Mycoplasma pulmonis, Pneumonia Virus of Mice, K Virus, Mouse Parvovirus, Mouse Hepatitis Virus, Mouse Norovirus, Mouse Minute Virus, Mouse Cytomegalovirus, Mouse Adenovirus, Lactate Dehydrogenase-Elevating Virus, Reovirus Panel, Lymphocytic Choriomeningitis Virus, Mouse Rotavirus.
Storage
(From the date of receipt)		 Store the undiluted solution at 4°C and avoid freeze-thaw cycle
Shipping Shipped under low temperature conditions
Sterility 0.2 μM filtered
Purity 99%
Protein concentration 6.36 mg/ml
Endotoxin Level ＜1EU/mg

カスタマーフィードバック

A2122-Anti-mouse PD-1 (CD279)-InVivo.gif

Selleckの高級品が、幾つかの出版された研究調査結果（以下を含む）で使われた：

Co-inhibition of PGF and VEGFA enhances the effectiveness of immunotherapy in bladder cancer [ International Journal of Medical Sciences, October 28, 2024, 21(15):2870-2882] PubMed: 39628692
EIF2B4 promotes hepatocellular carcinoma progression and immune evasion by driving STAT3 translation via a GEF-dependent mechanism [ Cellular Oncology, October 27, 2025, 48(6):1919-1933] PubMed: 41144132
Characteristics of tertiary lymphoid structures in prostate cancer and the impact of neoadjuvant therapy on their formation and maturation [ Frontiers in Immunology, November 4, 2025, 16:1663396] PubMed: 41262256
Yin Yang 1 Promotes Antiprogrammed Cell Death-1 Resistance in Hepatocellular Carcinoma through Polypeptide N-Acetylgalactosaminyltransferase 16-Mediated Glycosylation of Programmed Death Ligand-1 [ MedComm, November 26, 2025, 6(12):e70504] PubMed: 41322030
ZDHHC3-mediated SCAP S-acylation promotes cholesterol biosynthesis and tumor immune escape in hepatocellular carcinoma [ Cell Reports, November 1, 2024, 43(11):114962] PubMed: 39522165
Low-dose radiotherapy synergizes with PD-1 blockade to achieve durable survival in advanced NSCLC through antitumor neutrophil programming [ Signal Transduction and Targeted Therapy, May 7, 2026, 11(1):170] PubMed: 42091852
Betrixaban activates cGAS-STING to promote antitumor immunity without pathological inflammation [ EMBO Molecular Medicine, May 14, 2026, 18(6):2213-2235] PubMed: 42135568
CDK4/6 inhibitor abemaciclib combined with low-dose radiotherapy enhances the anti-tumor immune response to PD-1 blockade by inflaming the tumor microenvironment in Rb-deficient small cell lung cancer [ Translational Lung Cancer Research, May 1, 2024, 13(5):1032-1046] PubMed: 38854937
CCL5 hi CD4 + T Cells Regulate Macrophage Polarization and Promote Immunotherapy Response in Bladder Cancer [ Cancer Immunology Research, May 04, 2026, nan]
Oncolytic virus M1 reinvigorates CD8+ T-cell immunity against glioblastoma through B-cell-dependent antigen cross-presentation in the spleen [ Cellular and Molecular Immunology, March 4, 2026, 23(4):349-366] PubMed: 41781696

人間や獣医の診断であるか治療的な使用のためにでない。