Anti-mouse PD-1 (CD279)(29F.1A12)-InVivo [29F.1A12]

製品コード:A2165         Batch: A216507

印刷

Anti-mouse PD-1 (CD279)(29F.1A12)-InVivo [29F.1A12] reacts with mouse PD-1 (programmed death-1) also known as CD279. PD-1 is a 50-55 kDa cell surface receptor encoded by the Pdcd1 gene that belongs to the CD28 family of the Ig superfamily.

製品説明

Formulation PBS, pH 7.0 Contains no stabilizers or preservatives
Clone 29F.1A12
Isotype Rat IgG2a
Application in vivo blocking of PD-1/PD-L signaling in vitro PD-1 neutralization
Source CHO
Murine Pathogen Screening Panel all targets tested yielded Negative Results: Theiler’s Murine Encephalomyelitis Virus, Ectromelia (Mousepox) Virus, Hantavirus, Polyomavirus, Sendai Virus, Mycoplasma pulmonis, Pneumonia Virus of Mice, K Virus, Mouse Parvovirus, Mouse Hepatitis Virus, Mouse Norovirus, Mouse Minute Virus, Mouse Cytomegalovirus, Mouse Adenovirus, Lactate Dehydrogenase-Elevating Virus, Reovirus Panel, Lymphocytic Choriomeningitis Virus, Mouse Rotavirus.
Storage
(From the date of receipt)
Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles
Shipping Shipped under low temperature conditions
Sterility 0.2 μM filtered
Purity 99%
Protein concentration 4.93 mg/ml
Endotoxin Level <1EU/mg

Selleckの高級品が、幾つかの出版された研究調査結果(以下を含む)で使われた:

ALDH1L1 reverses CD8+ T cell exhaustion in the oral squamous cell carcinoma microenvironment by reprogramming L-glutamate metabolism [ Journal of Translational Medicine, February 7, 2026, 24(1):350] PubMed: 41654886
PD-L1-CD80 interactions are required for intracellular signaling necessary for dendritic cell migration [ Science Advances, 2025 Jan 31, eadt3044] PubMed: 39879305
PD-L1-CD80 interactions are required for intracellular signaling necessary for dendritic cell migration [ Sci Adv, 2025, 11(5):eadt3044] PubMed: 39879305

人間や獣医の診断であるか治療的な使用のためにでない。