Anti-mouse TNFα-InVivo

製品コード：A2124 Batch: A212405

Anti-mouse TNFα-InVivo reacts with mouse TNFα (tumor necrosis factor-alpha), a multifunctional proinflammatory cytokine. TNFα dysregulation is been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. TNFα knockout animals display defects in response to bacterial infection, characterized by defects in forming organized follicular dendritic cell networks and germinal centers with a lack of primary B cell follicles.

製品説明

Formulation	PBS, pH 8.0 Contains no stabilizers or preservatives
Clone	XT3.11
Isotype	Rat IgG1
Application	in vitro &in vivo TNFα neutralization, Western blot
Source	CHO
Murine Pathogen Screening Panel	all targets tested yielded Negative Results: Theiler’s Murine Encephalomyelitis Virus, Ectromelia (Mousepox) Virus, Hantavirus, Polyomavirus, Sendai Virus, Mycoplasma pulmonis, Pneumonia Virus of Mice, K Virus, Mouse Parvovirus, Mouse Hepatitis Virus, Mouse Norovirus, Mouse Minute Virus, Mouse Cytomegalovirus, Mouse Adenovirus, Lactate Dehydrogenase-Elevating Virus, Reovirus Panel, Lymphocytic Choriomeningitis Virus, Mouse Rotavirus.
Storage (From the date of receipt)	Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles
Shipping	Shipped under low temperature conditions
Sterility	0.2 μM filtered
Purity	99%
Protein concentration	10.22 mg/mL
Endotoxin Level	＜1 EU/mg

Selleckの高級品が、幾つかの出版された研究調査結果（以下を含む）で使われた：

Spatial and temporal single cell multi-omics in mice reveals macrophage-SFRP4+ stroma interactions promoting endometrial regeneration via TNF-α [ Cell Reports, June 1, 2026, 45(6):117434]	PubMed: 42234562
Neutralizing LFA-1 alleviates acute lung injury by diminishing pulmonary retention of CAR-T cells [ Pharmacological Research, August 1, 2026, 230:108292]	PubMed: 42285385
DNAM-1 immunoreceptor integrates innate and adaptive immune programs to drive intestinal inflammation [ bioRxiv, April 1, 2026, 2026.03.30.715436]

人間や獣医の診断であるか治療的な使用のためにでない。