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化学情報
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Synonyms | SDX105 | Storage (From the date of receipt) |
3 years -20°C powder |
| 化学式 | C16H21Cl2N3O2
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| 分子量 | 358.26 | CAS No. | 16506-27-7 | |
| Solubility (25°C)* | 体外 | DMSO | 72 mg/mL (200.97 mM) | |
| Ethanol | 7 mg/mL (19.53 mM) | |||
| Water | Insoluble | |||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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溶剤液（一定の濃度）を調合する
生物活性
| 製品説明 | Bendamustine is a nitrogen mustard drug used in the treatment of chronic lymphocytic leukemia (CLL), multiple myeloma, and non-Hodgkin's lymphoma. |
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プロトコル(参考用のみ)
Selleckの高級品が、幾つかの出版された研究調査結果（以下を含む）で使われた：
| Anti-tumor activity of selinexor in combination with antineoplastic agents in chronic lymphocytic leukemia [ Sci Rep, 2023, 13(1):16950] | PubMed: 37805613 |
| Anti-tumor activity of selinexor in combination with antineoplastic agents in chronic lymphocytic leukemia [ Sci Rep, 2023, 13(1):16950] | PubMed: 37805613 |
| The potential efficacy and mechanism of bendamustine in entra-nodal NK/T cell lymphoma [ Hematol Oncol, 2022, 10.1002/hon.3007] | PubMed: 35439335 |
| Glycoprotein PTGDS promotes tumorigenesis of diffuse large B-cell lymphoma by MYH9-mediated regulation of Wnt-β-catenin-STAT3 signaling [ Cell Death Differ, 2021, 10.1038/s41418-021-00880-2] | PubMed: 34743203 |
| Study of the antilymphoma activity of pracinostat reveals different sensitivities of DLBCL cells to HDAC inhibitors [ Blood Adv, 2021, 5(10):2467-2480] | PubMed: 33999145 |
| Regulatory Dendritic Cells Induced by Bendamustine Are Associated With Enhanced Flt3 Expression and Alloreactive T-Cell Death [ Front Immunol, 2021, 12:699128] | PubMed: 34249005 |
| Novel Peptide-drug Conjugate Melflufen Efficiently Eradicates Bortezomib-resistant Multiple Myeloma Cells Including Tumor-initiating Myeloma Progenitor Cells [ Hemasphere, 2021, 5(7):e602] | PubMed: 34136753 |
| Obinutuzumab in Combination with Chemotherapy Enhances Direct Cell Death in CD20-Positive Obinutuzumab-resistant Non-Hodgkin Lymphoma Cells [ Mol Cancer Ther, 2021, 10.1158/1535-7163.MCT-20-0864] | PubMed: 33850006 |
| Bendamustine Conditioning Skews Murine Host DCs Toward Pre-cDC1s and Reduces GvHD Independently of Batf3 [ Front Immunol, 2020, 11:1410] | PubMed: 32765499 |
| Supernumerary Incisors in CB6F1 Mice Conditioned with Chemotherapy and Total Body Irradiation before Bone Marrow Transplantation [ Comp Med, 2018, 68(5):349-352] | PubMed: 30208992 |
長期の保管のために-20°Cの下で製品を保ってください。
人間や獣医の診断であるか治療的な使用のためにでない。
各々の製品のための特定の保管と取扱い情報は、製品データシートの上で示されます。大部分のSelleck製品は、推薦された状況の下で安定です。製品は、推薦された保管温度と異なる温度で、時々出荷されます。長期の保管のために必要とされてそれと異なる温度で、多くの製品は、短期もので安定です。品質を維持するが、夜通しの積荷のために最も経済的な貯蔵状況を用いてあなたの送料を保存する状況の下に、製品が出荷されることを、我々は確実とします。製品の受領と同時に、製品データシートの上で貯蔵推薦に従ってください。