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Synonyms | N/A | Storage (From the date of receipt) |
3 years -20°C powder 1 years -80°C in solvent |
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化学式 | C9H9BrN2O3 |
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分子量 | 273.08 | CAS No. | 188011-69-0 | |
Solubility (25°C)* | 体外 | DMSO | 54 mg/mL (197.74 mM) | |
Water | Insoluble | |||
Ethanol | Insoluble | |||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
製品説明 | Bikinin is an ATP-competitive Arabidopsis GSK-3 inhibitor, and acts as a strong activator of brassinosteroid (BR) signaling. |
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in vitro | Bikinin directly targets BIN2 of Arabidopsis GSK-3s and activates brassinosteroid-dependent gene expression. [1] Bikinin also inhibits RD26 expression, and inhibits the induction of GUS activity by 150 mM NaCl in the RD26pro:GUS line. [3] |
in vivo | Bikinin strongly inhibits abscisic acid signaling outputs, and inhibits T180 phosphorylation of SnRK2.3 and its kinase activity in vivo. [2] |
キナーゼアッセイ | Kinase Assays | |
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The BIN2 kinase assay with GST-BIN2 and maltose binding protein (MaBP) fused to BES1 (MaBP-BES1) as a substrate is done as reported elsewhere. Kinase assays of the ASKs, AtMPK4 and AtMPK6 with myelin basic protein (MBP), AURORA1 with histone H3, and of the human kinases. Comparable activities of the different ASKs are used. For one particular kinase equal amounts (ranging from 20 to 100 ng depending on the innate kinase activity) are used in the assays with and without bikinin. |
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Control of grain size in rice by TGW3 phosphorylation of OsIAA10 through potentiation of OsIAA10-OsARF4-mediated auxin signaling [ Cell Rep, 2023, 42(3):112187] | PubMed: 36871218 |
The Histone Deacetylase 1/ GSK3/SHAGGY-Like Kinase 2/ BRASSINAZOLE RESISTANT 1 Module Controls Lateral Root Formation in Rice [ Plant Physiol, 2022, kiac015] | PubMed: 35078247 |
WRKY53 Integrates Classic Brassinosteroid Signaling and the Mitogen-Activated Protein Kinase Pathway to Regulate Rice Architecture and Seed Size [ Plant Cell, 2021, koab137] | PubMed: 34003966 |
長期の保管のために-20°Cの下で製品を保ってください。
人間や獣医の診断であるか治療的な使用のためにでない。
各々の製品のための特定の保管と取扱い情報は、製品データシートの上で示されます。大部分のSelleck製品は、推薦された状況の下で安定です。製品は、推薦された保管温度と異なる温度で、時々出荷されます。長期の保管のために必要とされてそれと異なる温度で、多くの製品は、短期もので安定です。品質を維持するが、夜通しの積荷のために最も経済的な貯蔵状況を用いてあなたの送料を保存する状況の下に、製品が出荷されることを、我々は確実とします。製品の受領と同時に、製品データシートの上で貯蔵推薦に従ってください。