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受注:045-509-1970 |
技術サポート:tech@selleck.co.jp 平日9:00〜18:00 1営業日以内にご連絡を差し上げます |
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Synonyms | SQ 14225,Capoten | Storage (From the date of receipt) |
3 years -20°C powder 1 years -80°C in solvent |
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| 化学式 | C9H15NO3S |
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| 分子量 | 217.29 | CAS No. | 62571-86-2 | ||||
| Solubility (25°C)* | 体外 | DMSO | 43 mg/mL (197.89 mM) | ||||
| Ethanol | 43 mg/mL (197.89 mM) | ||||||
| Water | 2 mg/mL (9.2 mM) | ||||||
| 体内 (毎回新しく調製した物を用意してください) |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| 製品説明 | Captopril (SQ 14225,Capoten) is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 6 nM. |
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| Ligand supplementation restores the cancer therapy efficacy of the antirheumatic drug auranofin from serum inactivation [ Nat Commun, 2025, 16(1):7347] | PubMed: 40783561 |
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| Comparative in vivo toxicology of ATR inhibitors ceralasertib, elimusertib, and berzosertib alone and in combination with ionizing radiation [ Toxicol Appl Pharmacol, 2025, 500:117375] | PubMed: 40339611 |
| Repurposing amiodarone for bladder cancer treatment [ Cancer Res Commun, 2025, 10.1158/2767-9764.CRC-24-0433] | PubMed: 40353763 |
| Molecular Signature Predictive of Long-Term Liver Fibrosis Progression to Inform Antifibrotic Drug Development [ Gastroenterology, 2022, 162(4):1210-1225] | PubMed: 34951993 |
| Effect of Angiotensin-Converting-Enzyme Inhibitor and Angiotensin II Receptor Antagonist Treatment on ACE2 Expression and SARS-CoV-2 Replication in Primary Airway Epithelial Cells [ Front Pharmacol, 2021, 12:765951] | PubMed: 34867390 |
| Strain-Dependent Variability of Early Discovery Small Molecule Pharmacokinetics in Mice: Does Strain Matter? [ Drug Metab Dispos, 2020, 48(8):613-621] | PubMed: 32474442 |
| Calcilytic NPS2143 promotes proliferation and inhibits apoptosis of spontaneously hypertensive rat vascular smooth muscle cells via activation of the renin-angiotensin system [ Exp Ther Med, 2020, 20(2):818-829] | PubMed: 32742325 |
| The efficacy of a coordinated pharmacological blockade in glioblastoma stem cells with nine repurposed drugs using the CUSP9 strategy. [ J Cancer Res Clin Oncol, 2019, 145(6):1495-1507] | PubMed: 31028540 |
| CaSR participates in the regulation of vascular tension in the mesentery of hypertensive rats via the PLC‑IP3/AC‑V/cAMP/RAS pathway [ Mol Med Rep, 2019, 20(5):4433-4448] | PubMed: 31485595 |
長期の保管のために-20°Cの下で製品を保ってください。
人間や獣医の診断であるか治療的な使用のためにでない。
各々の製品のための特定の保管と取扱い情報は、製品データシートの上で示されます。大部分のSelleck製品は、推薦された状況の下で安定です。製品は、推薦された保管温度と異なる温度で、時々出荷されます。長期の保管のために必要とされてそれと異なる温度で、多くの製品は、短期もので安定です。品質を維持するが、夜通しの積荷のために最も経済的な貯蔵状況を用いてあなたの送料を保存する状況の下に、製品が出荷されることを、我々は確実とします。製品の受領と同時に、製品データシートの上で貯蔵推薦に従ってください。